About   Help   FAQ
Has1
Gene Detail
Symbol

Name
ID
Has1
hyaluronan synthase1
MGI:106590
Feature Type
protein coding gene
Genetic Map
Chromosome 17
10.53 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr17:17843328-17855188 bp, - strand
From Ensembl annotation of GRCm38

  11861 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1165  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 dog; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: HAS1
Gene Tree: Has1

Human
homologs
HAS1, hyaluronan synthase 1
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 3036
neXtProt AC: NX_Q92839

Human Synonyms: HAS

Human Chr (Location): 19q13.4; chr19:51713112-51723992 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele are viable and appear grossly normal.
 
Interactions
Has1 interacts with 47 markers (Mir15a, Mir15b, Mir16-1, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (3 records)
Data Summary: Results (94)    Tissues (94)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
cDNA source data(7)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase has1 ; ZFIN has1    NEW 
Molecular
reagents
All nucleic(8) Genomic(1) cDNA(7)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000003665 (Evidence)
Entrez Gene 15116 (Evidence)
UniGene 255701
DFCI TC1588977
DoTS DT.87040281, DT.91557173
NIA Mouse Gene Index U037463
EC 2.4.1.212
Consensus CDS Project CCDS37459.1
International Mouse Phenotyping Consortium Status Has1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000003665 Ensembl Gene Model | MGI Sequence Detail 11861 C57BL/6J ±  kb
transcript ENSMUST00000003762 Ensembl | MGI Sequence Detail 2090 Not Applicable 
polypeptide ENSMUSP00000003762 Ensembl | MGI Sequence Detail 583 Not Applicable 

For the selected sequences
All sequences(22) RefSeq(4) UniProt(4)
Polymorphisms
RFLP(1) : SNPs within 2kb(294 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR026107 Hyaluronan synthase/nodulation protein C
Protein Ontology PR:000008449 hyaluronan synthase 1
References
(Earliest) J:5771 Holmes RS, Genetics of peroxisomal enzymes in the mouse: nonlinkage of D-amino acid oxidase locus (Dao) to catalase (Cs) and L-alpha-hydroxyacid oxidase (Hao-1) loci on chromosome 2. Biochem Genet. 1976 Dec;14(11-12):981-7
(Latest) J:219524 Akgul Y, et al., Hyaluronan in cervical epithelia protects against infection-mediated preterm birth. J Clin Invest. 2014 Dec;124(12):5481-9
All references(45)
Other
accession IDs
MGD-MRK-35046

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/23/2015
MGI 5.22
The Jackson Laboratory