Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HLA-DOA
  • Mouse genes H2-Oa
  • Rat genes RT1-DOa
  • Zfish genes mhc2d8.35a1,mhc2d8.37a1,mhc2d8.46a,mhc2dga,si:busm1-194e12.8,zgc:123107
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set H2-Oa

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0023026	MHC class II protein complex binding	HLA-DOA	IDA		Human	PMID:22733780
Molecular Function	GO:0005515	protein binding	HLA-DOA	IPI	UniProtKB:Q04864	Human	PMID:25416956
Cellular Component	GO:0042613	MHC class II protein complex	HLA-DOA	IDA		Human	PMID:22733780
Biological Process	GO:0019882	antigen processing and presentation	H2-Oa	IMP	MGI:MGI:2386294	Mouse	PMID:11069069
Biological Process	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	H2-Oa	IMP	MGI:MGI:2675254	Mouse	PMID:9492004
Biological Process	GO:0002587	negative regulation of antigen processing and presentation of peptide antigen via MHC class II	HLA-DOA	IDA		Human	PMID:22733780
Biological Process	GO:0045580	regulation of T cell differentiation	H2-Oa	IMP	MGI:MGI:2386294	Mouse	PMID:11069069

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern