Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GUCY2F
  • Mouse genes Gucy2f
  • Rat genes Gucy2f
  • Zfish genes gc2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gucy2f

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004383	guanylate cyclase activity	Gucy2f	IDA		Rat	PMID:7831337|RGD:632891
Molecular Function	GO:0042802	identical protein binding	Gucy2f	IPI	RGD:620439	Rat	PMID:9153227|RGD:1599625
Molecular Function	GO:0005515	protein binding	Gucy2f	IPI	UniProtKB:Q8BRE0	Mouse	MGI:MGI:4867355|PMID:21078983
Molecular Function	GO:0044877	protein-containing complex binding	Gucy2f	IPI	RGD:620438	Rat	PMID:9153227|RGD:1599625
Cellular Component	GO:0016020	membrane	Gucy2f	IDA		Rat	PMID:7831337|RGD:632891
Cellular Component	GO:0005886	plasma membrane	Gucy2f	IDA		Rat	PMID:7831337|RGD:632891
Cellular Component	GO:0005886	plasma membrane	Gucy2f	IDA		Rat	PMID:9153227|RGD:1599625
Cellular Component	GO:0120200	rod photoreceptor outer segment	Gucy2f	IDA		Mouse	MGI:MGI:4867355|PMID:21078983
Biological Process	GO:0019934	cGMP-mediated signaling	Gucy2f	IDA		Rat	PMID:9153227|RGD:1599625
Biological Process	GO:0050908	detection of light stimulus involved in visual perception	Gucy2f	IMP		Mouse	MGI:MGI:3708225|PMID:17255100

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern