Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GSTM3
  • Mouse genes Gstm5
  • Rat genes Gstm5
  • Zfish genes gstm.1,gstm.2,gstm.3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gstm5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019899	enzyme binding	GSTM3	IPI	UniProtKB:P21266	Human	PMID:8373352
Molecular Function	GO:0043295	glutathione binding	GSTM3	IDA		Human	PMID:8373352
Molecular Function	GO:0004364	glutathione transferase activity	GSTM3	IDA		Human	PMID:10587441
Molecular Function	GO:0004364	glutathione transferase activity	GSTM3	IDA		Human	PMID:8373352
Molecular Function	GO:0004364	glutathione transferase activity	GSTM3	IDA		Human	PMID:9545290
Molecular Function	GO:0004364	glutathione transferase activity	Gstm5	IDA		Mouse	PMID:9545290
Molecular Function	GO:0004364	glutathione transferase activity	Gstm5	IDA		Rat	PMID:9545290|RGD:61624
Molecular Function	GO:0004364	glutathione transferase activity	gstm.1	IDA		Zfish	PMID:25461745
Molecular Function	GO:0004364	glutathione transferase activity	gstm.3	IDA		Zfish	PMID:25461745
Molecular Function	GO:0042802	identical protein binding	GSTM3	IPI	UniProtKB:P21266	Human	PMID:16189514
Molecular Function	GO:0042802	identical protein binding	GSTM3	IPI	UniProtKB:P21266	Human	PMID:19060904
Molecular Function	GO:0042802	identical protein binding	GSTM3	IPI	UniProtKB:P21266	Human	PMID:21516116
Molecular Function	GO:0042802	identical protein binding	GSTM3	IPI	UniProtKB:P21266	Human	PMID:31515488
Molecular Function	GO:0042802	identical protein binding	GSTM3	IPI	UniProtKB:P21266	Human	PMID:32296183
Molecular Function	GO:0042802	identical protein binding	Gstm5	IPI	PR:P48774	Mouse	PMID:9545290
Molecular Function	GO:0042802	identical protein binding	Gstm5	IDA		Rat	PMID:9545290|RGD:61624
Molecular Function	GO:0005515	protein binding	GSTM3	IPI	UniProtKB:P21754	Human	PMID:23355646
Molecular Function	GO:0005515	protein binding	GSTM3	IPI	UniProtKB:Q12836	Human	PMID:23355646
Molecular Function	GO:0005515	protein binding	GSTM3	IPI	UniProtKB:P46439	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	GSTM3	IPI	UniProtKB:P46439	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	GSTM3	IPI	UniProtKB:Q03013	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	GSTM3	IPI	UniProtKB:P46439	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GSTM3	IPI	UniProtKB:Q03013	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GSTM3	IPI	UniProtKB:Q5SYC1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Gstm5	IPI	MGI:MGI:97548	Mouse	PMID:19889946
Molecular Function	GO:0042803	protein homodimerization activity	GSTM3	IPI	UniProtKB:P21266	Human	PMID:8373352
Molecular Function	GO:0042803	protein homodimerization activity	GSTM3	IDA		Human	PMID:9545290
Cellular Component	GO:0005737	cytoplasm	GSTM3	IDA		Human	PMID:8373352
Cellular Component	GO:0005829	cytosol	GSTM3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	GSTM3	HDA		Human	PMID:23533145
Cellular Component	GO:0045171	intercellular bridge	GSTM3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	GSTM3	HDA		Human	PMID:21630459
Cellular Component	GO:0035686	sperm fibrous sheath	Gstm5	IDA		Mouse	PMID:16687649
Cellular Component	GO:0035686	sperm fibrous sheath	Gstm5	IDA		Mouse	PMID:19889946
Biological Process	GO:0070458	cellular detoxification of nitrogen compound	GSTM3	IDA		Human	PMID:8373352
Biological Process	GO:0006749	glutathione metabolic process	GSTM3	IDA		Human	PMID:10587441
Biological Process	GO:0006749	glutathione metabolic process	GSTM3	IDA		Human	PMID:8373352
Biological Process	GO:0018916	nitrobenzene metabolic process	GSTM3	IDA		Human	PMID:8373352
Biological Process	GO:0043627	response to estrogen	GSTM3	IEP		Human	PMID:10037815
Biological Process	GO:0042178	xenobiotic catabolic process	GSTM3	IDA		Human	PMID:8373352

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern