Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GRK1
  • Mouse genes Grk1
  • Rat genes Grk1
  • Zfish genes grk1a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Grk1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0050254	rhodopsin kinase activity	GRK1	IDA		Human	PMID:15946941
Molecular Function	GO:0050254	rhodopsin kinase activity	Grk1	IDA		Rat	PMID:2402884|RGD:1600006
Molecular Function	GO:0050254	rhodopsin kinase activity	grk1a	IDA		Zfish	PMID:16787417
Cellular Component	GO:0001750	photoreceptor outer segment	Grk1	IDA		Mouse	PMID:22183407
Biological Process	GO:0006915	apoptotic process	Grk1	IMP	MGI:MGI:2668595	Mouse	PMID:10097103
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Grk1	IMP	MGI:MGI:2668595	Mouse	PMID:10097103
Biological Process	GO:0016310	phosphorylation	Grk1	IMP	MGI:MGI:2668595	Mouse	PMID:10097103
Biological Process	GO:0008594	photoreceptor cell morphogenesis	Grk1	IMP	MGI:MGI:2668595	Mouse	PMID:10097103
Biological Process	GO:0042327	positive regulation of phosphorylation	Grk1	IMP	MGI:MGI:2668595	Mouse	PMID:10097103
Biological Process	GO:0060060	post-embryonic retina morphogenesis in camera-type eye	Grk1	IMP	MGI:MGI:2668595	Mouse	PMID:10097103
Biological Process	GO:0046777	protein autophosphorylation	GRK1	IMP		Human	PMID:15946941
Biological Process	GO:0046777	protein autophosphorylation	Grk1	IDA		Rat	PMID:1550556|RGD:1600005
Biological Process	GO:0022400	regulation of rhodopsin mediated signaling pathway	GRK1	IDA		Human	PMID:15946941
Biological Process	GO:0009416	response to light stimulus	Grk1	IMP	MGI:MGI:2668595	Mouse	PMID:10097103
Biological Process	GO:0009416	response to light stimulus	Grk1	IEP		Rat	PMID:3950623|RGD:1600007
Biological Process	GO:0009410	response to xenobiotic stimulus	Grk1	IEP		Rat	PMID:11923229|RGD:1600003
Biological Process	GO:0097473	retinal rod cell apoptotic process	Grk1	IMP	MGI:MGI:2668595	Mouse	PMID:10097103

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern