Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GRIK4
  • Mouse genes Grik4
  • Rat genes Grik4
  • Zfish genes grik4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Grik4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	GRIK4	IDA		Human	PMID:20026616
Molecular Function	GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	GRIK4	IMP		Human	PMID:20026616
Molecular Function	GO:0005515	protein binding	Grik4	IPI	PR:P39087	Mouse	PMID:12954862
Molecular Function	GO:0005515	protein binding	Grik4	IPI	PR:Q8R4I7	Mouse	PMID:21734292
Molecular Function	GO:0005515	protein binding	Grik4	IPI	PR:Q61626	Mouse	PMID:12954862
Cellular Component	GO:0030424	axon	Grik4	IDA		Rat	PMID:15844209|RGD:1642495
Cellular Component	GO:0030425	dendrite	Grik4	IDA		Rat	PMID:15844209|RGD:1642495
Cellular Component	GO:0098978	glutamatergic synapse	Grik4	IDA		Rat	PMID:16360275|RGD:1642473
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	Grik4	IDA		Mouse	PMID:12954862
Cellular Component	GO:0032983	kainate selective glutamate receptor complex	Grik4	IPI	PR:P39087	Mouse	PMID:12954862
Cellular Component	GO:0032983	kainate selective glutamate receptor complex	Grik4	IPI	PR:Q61626	Mouse	PMID:12954862
Cellular Component	GO:0016020	membrane	Grik4	IDA		Mouse	PMID:12954862
Cellular Component	GO:0005634	nucleus	Grik4	IDA		Rat	PMID:16360275|RGD:1642473
Cellular Component	GO:0043204	perikaryon	Grik4	IDA		Rat	PMID:15844209|RGD:1642495
Cellular Component	GO:0045211	postsynaptic membrane	Grik4	IDA		Mouse	PMID:12954862
Cellular Component	GO:0042734	presynaptic membrane	Grik4	IDA		Mouse	PMID:12954862
Cellular Component	GO:0042734	presynaptic membrane	Grik4	IDA		Rat	PMID:16360275|RGD:1642473
Cellular Component	GO:0045202	synapse	Grik4	IDA		Mouse	PMID:21734292
Cellular Component	GO:0043195	terminal bouton	Grik4	IDA		Rat	PMID:15844209|RGD:1642495
Cellular Component	GO:0043195	terminal bouton	Grik4	IDA		Rat	PMID:16360275|RGD:1642473
Biological Process	GO:0031960	response to corticosteroid	Grik4	IEP		Rat	PMID:19180187|RGD:2316517

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern