Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GRB7
  • Mouse genes Grb7
  • Rat genes Grb7
  • Zfish genes grb7
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Grb7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	GRB7	IPI	UniProtKB:Q14451	Human	PMID:15841400
Molecular Function	GO:0035091	phosphatidylinositol binding	GRB7	IDA		Human	PMID:12021278
Molecular Function	GO:0005515	protein binding	GRB7	IPI	UniProtKB:P10721	Human	PMID:10377264
Molecular Function	GO:0005515	protein binding	GRB7	IPI	UniProtKB:Q92730	Human	PMID:10664463
Molecular Function	GO:0005515	protein binding	GRB7	IPI	UniProtKB:P04626	Human	PMID:12061724
Molecular Function	GO:0005515	protein binding	GRB7	IPI	UniProtKB:P54762	Human	PMID:12223469
Molecular Function	GO:0005515	protein binding	GRB7	IPI	UniProtKB:Q5SQ64	Human	PMID:12852788
Molecular Function	GO:0005515	protein binding	GRB7	IPI	UniProtKB:P04626	Human	PMID:12975581
Molecular Function	GO:0005515	protein binding	GRB7	IPI	UniProtKB:P62157	Human	PMID:15806159
Molecular Function	GO:0005515	protein binding	GRB7	IPI	UniProtKB:P04626	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	GRB7	IPI	UniProtKB:P21860	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	GRB7	IPI	UniProtKB:O00165	Human	PMID:20665473
Molecular Function	GO:0005515	protein binding	GRB7	IPI	UniProtKB:P21860	Human	PMID:24189400
Molecular Function	GO:0005515	protein binding	GRB7	IPI	UniProtKB:P10275	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	GRB7	IPI	UniProtKB:P10721	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	GRB7	IPI	UniProtKB:Q8IWV1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GRB7	IPI	UniProtKB:Q8NC69	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GRB7	IPI	UniProtKB:Q9NQ86	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GRB7	IPI	UniProtKB:Q05397	Human	PMID:25814554
Molecular Function	GO:0005515	protein binding	GRB7	IPI	UniProtKB:Q8TAK6	Human	PMID:25814554
Molecular Function	GO:0005515	protein binding	GRB7	IPI	UniProtKB:Q8IWV1	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	GRB7	IPI	UniProtKB:P09619	Human	PMID:8940081
Molecular Function	GO:0005515	protein binding	GRB7	IPI	UniProtKB:P04626	Human	PMID:9079677
Molecular Function	GO:0005515	protein binding	GRB7	IPI	UniProtKB:P21860	Human	PMID:9516479
Molecular Function	GO:0005515	protein binding	Grb7	IPI	UniProtKB:P70372|UniProtKB:Q80ZW7	Mouse	MGI:MGI:5284766|PMID:18273060
Molecular Function	GO:0005515	protein binding	Grb7	IPI	UniProtKB:Q02858	Mouse	MGI:MGI:5508745|PMID:10521483
Molecular Function	GO:0005515	protein binding	Grb7	IPI	UniProtKB:Q03135	Mouse	MGI:MGI:5508743|PMID:11075810
Molecular Function	GO:0005515	protein binding	Grb7	IPI	UniProtKB:P00533	Rat	PMID:31585087|RGD:21201274
Molecular Function	GO:0019901	protein kinase binding	GRB7	IDA		Human	PMID:12021278
Cellular Component	GO:0010494	cytoplasmic stress granule	Grb7	IDA		Mouse	MGI:MGI:5284766|PMID:18273060
Cellular Component	GO:0005829	cytosol	GRB7	IDA		Human	PMID:10893408
Cellular Component	GO:0005829	cytosol	GRB7	IDA		Human	PMID:12021278
Cellular Component	GO:0005925	focal adhesion	GRB7	IDA		Human	PMID:10893408
Cellular Component	GO:0005925	focal adhesion	GRB7	IDA		Human	PMID:12021278
Biological Process	GO:0017148	negative regulation of translation	Grb7	IMP		Mouse	MGI:MGI:5284766|PMID:18273060
Biological Process	GO:0030335	positive regulation of cell migration	GRB7	IDA		Human	PMID:10893408
Biological Process	GO:0030335	positive regulation of cell migration	GRB7	IDA		Human	PMID:12021278
Biological Process	GO:0034063	stress granule assembly	Grb7	IMP		Mouse	MGI:MGI:5284766|PMID:18273060

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern