Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GPR89A,GPR89B
  • Mouse genes Gpr89
  • Rat genes Gpr89b
  • Zfish genes si:ch73-390b10.2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gpr89

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	GPR89B	IPI	UniProtKB:O76024	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Gpr89	IPI	UniProtKB:Q9D4V7	Mouse	MGI:MGI:6405642|PMID:32220963
Molecular Function	GO:0008308	voltage-gated monoatomic anion channel activity	GPR89A	IDA		Human	PMID:18794847
Cellular Component	GO:0032580	Golgi cisterna membrane	GPR89A	IDA		Human	PMID:18794847
Cellular Component	GO:0030660	Golgi-associated vesicle membrane	GPR89A	IDA		Human	PMID:18794847
Biological Process	GO:0051452	intracellular pH reduction	GPR89A	IDA		Human	PMID:18794847
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	GPR89A	HMP		Human	PMID:12761501
Biological Process	GO:0043588	skin development	Gpr89	IMP	MGI:MGI:1926815,MGI:MGI:5446388	Mouse	PMID:22572823
Biological Process	GO:0030217	T cell differentiation	Gpr89	IMP		Mouse	MGI:MGI:6405642|PMID:32220963

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern