Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GPAM
  • Mouse genes Gpam
  • Rat genes Gpam
  • Zfish genes gpam
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gpam

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004366	glycerol-3-phosphate O-acyltransferase activity	GPAM	EXP		Human	PMID:18238778
Molecular Function	GO:0004366	glycerol-3-phosphate O-acyltransferase activity	GPAM	IMP		Human	PMID:18238778
Molecular Function	GO:0004366	glycerol-3-phosphate O-acyltransferase activity	GPAM	IMP		Human	PMID:19075029
Molecular Function	GO:0004366	glycerol-3-phosphate O-acyltransferase activity	Gpam	IMP	MGI:MGI:2669956	Mouse	PMID:12417724
Molecular Function	GO:0004366	glycerol-3-phosphate O-acyltransferase activity	Gpam	IMP	MGI:MGI:3785381	Mouse	PMID:18339309
Molecular Function	GO:0004366	glycerol-3-phosphate O-acyltransferase activity	Gpam	IDA		Mouse	PMID:15152008
Molecular Function	GO:0004366	glycerol-3-phosphate O-acyltransferase activity	Gpam	IMP		Mouse	PMID:16935266
Molecular Function	GO:0004366	glycerol-3-phosphate O-acyltransferase activity	Gpam	IDA		Mouse	PMID:12417724
Molecular Function	GO:0004366	glycerol-3-phosphate O-acyltransferase activity	Gpam	IDA		Rat	PMID:10446428|RGD:61613
Molecular Function	GO:0004366	glycerol-3-phosphate O-acyltransferase activity	Gpam	IMP		Rat	PMID:22905194|RGD:30309909
Molecular Function	GO:0005515	protein binding	GPAM	IPI	UniProtKB:Q9UHD4	Human	PMID:32296183
Cellular Component	GO:0005743	mitochondrial inner membrane	Gpam	HDA		Mouse	PMID:12865426
Cellular Component	GO:0031966	mitochondrial membrane	Gpam	IDA		Rat	PMID:18167308|RGD:2313661
Cellular Component	GO:0005741	mitochondrial outer membrane	Gpam	IMP	MGI:MGI:3785384	Mouse	PMID:18339309
Cellular Component	GO:0005741	mitochondrial outer membrane	Gpam	IDA		Rat	PMID:17493869|RGD:2313662
Cellular Component	GO:0005739	mitochondrion	Gpam	IDA		Mouse	PMID:12417724
Cellular Component	GO:0005739	mitochondrion	Gpam	IMP	MGI:MGI:3785381	Mouse	PMID:18339309
Cellular Component	GO:0005739	mitochondrion	Gpam	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Gpam	HDA		Mouse	PMID:14651853
Biological Process	GO:0050798	activated T cell proliferation	Gpam	IMP	MGI:MGI:2669956	Mouse	PMID:18971390
Biological Process	GO:0006924	activation-induced cell death of T cells	Gpam	IMP	MGI:MGI:2669956	Mouse	PMID:18971390
Biological Process	GO:0006637	acyl-CoA metabolic process	Gpam	IMP	MGI:MGI:2669956	Mouse	PMID:15878874
Biological Process	GO:0032869	cellular response to insulin stimulus	Gpam	IDA		Rat	PMID:18167308|RGD:2313661
Biological Process	GO:0051607	defense response to virus	Gpam	IMP	MGI:MGI:2669956	Mouse	PMID:19193813
Biological Process	GO:0006651	diacylglycerol biosynthetic process	Gpam	IMP		Rat	PMID:22905194|RGD:30309909
Biological Process	GO:0055089	fatty acid homeostasis	Gpam	IMP	MGI:MGI:2669956	Mouse	PMID:18522808
Biological Process	GO:0006631	fatty acid metabolic process	Gpam	IMP	MGI:MGI:2669956	Mouse	PMID:12417724
Biological Process	GO:0006650	glycerophospholipid metabolic process	Gpam	IMP	MGI:MGI:2669956	Mouse	PMID:18971390
Biological Process	GO:0032623	interleukin-2 production	Gpam	IMP	MGI:MGI:2669956	Mouse	PMID:18971390
Biological Process	GO:0070236	negative regulation of activation-induced cell death of T cells	Gpam	IMP	MGI:MGI:2669956	Mouse	PMID:18971390
Biological Process	GO:0006654	phosphatidic acid biosynthetic process	Gpam	IMP		Rat	PMID:22905194|RGD:30309909
Biological Process	GO:0006655	phosphatidylglycerol biosynthetic process	GPAM	IMP		Human	PMID:19075029
Biological Process	GO:0055091	phospholipid homeostasis	Gpam	IMP	MGI:MGI:2669956	Mouse	PMID:18522808
Biological Process	GO:0042104	positive regulation of activated T cell proliferation	Gpam	IMP	MGI:MGI:2669956	Mouse	PMID:18971390
Biological Process	GO:0040018	positive regulation of multicellular organism growth	Gpam	IMP	MGI:MGI:2669956	Mouse	PMID:12417724
Biological Process	GO:0010867	positive regulation of triglyceride biosynthetic process	Gpam	IDA		Rat	PMID:15598672|RGD:2313665
Biological Process	GO:0001817	regulation of cytokine production	Gpam	IMP	MGI:MGI:2669956	Mouse	PMID:18971390
Biological Process	GO:0014823	response to activity	Gpam	IDA		Rat	PMID:16234267|RGD:2313664
Biological Process	GO:0046686	response to cadmium ion	Gpam	IEP		Rat	PMID:17066326|RGD:2313663
Biological Process	GO:0009750	response to fructose	Gpam	IEP		Rat	PMID:19053045|RGD:2313651
Biological Process	GO:0009749	response to glucose	Gpam	IMP	MGI:MGI:2669956	Mouse	PMID:16054099
Biological Process	GO:0009749	response to glucose	Gpam	IMP	MGI:MGI:2669956	Mouse	PMID:15878874
Biological Process	GO:0031667	response to nutrient levels	Gpam	IEP		Rat	PMID:18493788|RGD:2313653
Biological Process	GO:0019432	triglyceride biosynthetic process	GPAM	IDA		Human	PMID:18238778
Biological Process	GO:0019432	triglyceride biosynthetic process	Gpam	IMP	MGI:MGI:2669956	Mouse	PMID:12417724
Biological Process	GO:0006641	triglyceride metabolic process	Gpam	IMP	MGI:MGI:2669956	Mouse	PMID:15878874
Biological Process	GO:0006641	triglyceride metabolic process	Gpam	IMP	MGI:MGI:2669956	Mouse	PMID:18522808
Biological Process	GO:0006641	triglyceride metabolic process	Gpam	IMP		Mouse	PMID:16935266

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern