About   Help   FAQ
Gpam
Gene Detail
Symbol

Name
ID
Gpam
glycerol-3-phosphate acyltransferase, mitochondrial
MGI:109162
Synonyms
GPAT1
Feature Type
protein coding gene
Genetic Map
Chromosome 19
50.81 cM
Detailed Genetic Map ± 1 cM


Mapping data(6)
Sequence Map
Chr19:55069734-55099451 bp, - strand
From VEGA annotation of GRCm38

  29718 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7343  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: glycerol-3-phosphate O-acyltransferase/dihydroxyacetone phosphate acyltransferase
Gene Tree: Gpam

Human
homologs
Human Homolog GPAM, glycerol-3-phosphate acyltransferase, mitochondrial
NCBI Gene ID 57678
neXtProt AC  NX_Q9HCL2
Human Synonyms  GPAT, GPAT1
Human Chr (Location)  10q25.2; chr10:112148213-112215395 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Targeted(7)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutant mice weighed less than controls and showed reduced triacylglycerol levels in the liver and plasma. The glycerolipid fatty acid composition is also disrupted in mutant mice.
 
Interactions
Gpam interacts with 182 markers (Mir1b, Mir15a, Mir15b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (4 records)
Data Summary: Results (199)    Tissues (150)    Images (41)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 199
cDNA source data(57)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(60) Genomic(1) cDNA(57) Primer pair(1) Other(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000033406 (Evidence)
Ensembl Gene ModelENSMUSG00000024978 (Evidence)
Entrez Gene14732 (Evidence)
UniGene210196
DFCITC1582412, TC1603341, TC1628149, TC1642645
DoTSDT.102557304, DT.55154483, DT.91383273, DT.91482487
NIA Mouse Gene IndexU039161
EC2.3.1.15
Consensus CDS ProjectCCDS29906.1
International Mouse Knockout Project StatusGpam
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000033406 VEGA Gene Model | MGI Sequence Detail 29718 C57BL/6J ±  kb
transcript OTTMUST00000083871 VEGA | MGI Sequence Detail 3832 Not Applicable 
polypeptide OTTMUSP00000045122 VEGA | MGI Sequence Detail 827 Not Applicable 

For the selected sequences
All sequences(35) RefSeq(9) UniProt(2)
Polymorphisms
RFLP(1) : SNPs within 2kb(232 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR022284 Glycerol-3-phosphate O-acyltransferase
InterPro IPR002123 Phospholipid/glycerol acyltransferase
Protein Ontology PR:000008159 glycerol-3-phosphate acyltransferase 1, mitochondrial
References
(Earliest) J:24536 Shin DH, et al., Transcriptional regulation of p90 with sequence homology to Escherichia coli glycerol-3-phosphate acyltransferase. J Biol Chem. 1991 Dec 15;266(35):23834-9
(Latest) J:203532 Park YK, et al., Hypoxia-inducible factor-2alpha-dependent hypoxic induction of Wnt10b expression in adipogenic cells. J Biol Chem. 2013 Sep 6;288(36):26311-22
All references(59)
Other
accession IDs
MGD-MRK-38206

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/08/2014
MGI 5.20
The Jackson Laboratory