Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GLO1
  • Mouse genes Glo1
  • Rat genes Glo1
  • Zfish genes glo1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Glo1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004462	lactoylglutathione lyase activity	GLO1	IDA		Human	PMID:11489834
Molecular Function	GO:0004462	lactoylglutathione lyase activity	GLO1	IDA		Human	PMID:20454679
Molecular Function	GO:0004462	lactoylglutathione lyase activity	GLO1	IDA		Human	PMID:23122816
Molecular Function	GO:0004462	lactoylglutathione lyase activity	GLO1	IDA		Human	PMID:9705294
Molecular Function	GO:0004462	lactoylglutathione lyase activity	Glo1	IDA		Mouse	MGI:MGI:5526937|PMID:18695250
Molecular Function	GO:0004462	lactoylglutathione lyase activity	Glo1	IDA		Mouse	PMID:1914521
Molecular Function	GO:0004462	lactoylglutathione lyase activity	Glo1	IDA		Mouse	PMID:22171037
Molecular Function	GO:0004462	lactoylglutathione lyase activity	Glo1	IDA		Mouse	PMID:566476
Molecular Function	GO:0004462	lactoylglutathione lyase activity	Glo1	IDA		Mouse	PMID:910130
Molecular Function	GO:0004462	lactoylglutathione lyase activity	Glo1	IDA		Mouse	PMID:7444718
Molecular Function	GO:0004462	lactoylglutathione lyase activity	Glo1	IDA		Mouse	PMID:7333654
Molecular Function	GO:0004462	lactoylglutathione lyase activity	Glo1	IDA		Mouse	PMID:7323947
Molecular Function	GO:0004462	lactoylglutathione lyase activity	Glo1	IDA		Rat	PMID:10712823|RGD:1627641
Molecular Function	GO:0004462	lactoylglutathione lyase activity	Glo1	IDA		Rat	PMID:8719777|RGD:1641958
Molecular Function	GO:0004462	lactoylglutathione lyase activity	Glo1	IDA		Rat	PMID:8903102|RGD:1641959
Molecular Function	GO:0004462	lactoylglutathione lyase activity	glo1	IMP	ZFIN:ZDB-GENO-200507-65	Zfish	PMID:31217350
Molecular Function	GO:0005515	protein binding	GLO1	IPI	UniProtKB:Q3MIT2	Human	PMID:32296183
Molecular Function	GO:0008270	zinc ion binding	GLO1	IDA		Human	PMID:23122816
Molecular Function	GO:0008270	zinc ion binding	GLO1	IDA		Human	PMID:9705294
Molecular Function	GO:0008270	zinc ion binding	Glo1	IDA		Mouse	MGI:MGI:5526937|PMID:18695250
Cellular Component	GO:0005829	cytosol	GLO1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	GLO1	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	GLO1	HDA		Human	PMID:23533145
Cellular Component	GO:0005654	nucleoplasm	GLO1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	GLO1	IDA		Human	GO_REF:0000052
Biological Process	GO:0005975	carbohydrate metabolic process	Glo1	IDA		Rat	PMID:8719777|RGD:1641958
Biological Process	GO:0005975	carbohydrate metabolic process	Glo1	IDA		Rat	PMID:8903102|RGD:1641959
Biological Process	GO:0006749	glutathione metabolic process	Glo1	IDA		Rat	PMID:8719777|RGD:1641958
Biological Process	GO:0006749	glutathione metabolic process	Glo1	IDA		Rat	PMID:8903102|RGD:1641959
Biological Process	GO:0009438	methylglyoxal metabolic process	Glo1	IDA		Rat	PMID:10712823|RGD:1627641
Biological Process	GO:0009438	methylglyoxal metabolic process	Glo1	IDA		Rat	PMID:8719777|RGD:1641958
Biological Process	GO:0009438	methylglyoxal metabolic process	Glo1	IDA		Rat	PMID:8903102|RGD:1641959
Biological Process	GO:0043066	negative regulation of apoptotic process	GLO1	IMP		Human	PMID:10807791
Biological Process	GO:0043066	negative regulation of apoptotic process	GLO1	IDA		Human	PMID:11489834
Biological Process	GO:0030316	osteoclast differentiation	Glo1	IMP		Mouse	MGI:MGI:5526937|PMID:18695250
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Glo1	IDA		Mouse	PMID:17670746

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern