Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GIGYF2
  • Mouse genes Gigyf2
  • Rat genes Gigyf2
  • Zfish genes gigyf2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gigyf2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	GIGYF2	HDA		Human	PMID:25468996
Molecular Function	GO:0070064	proline-rich region binding	GIGYF2	IDA		Human	PMID:20696395
Molecular Function	GO:0005515	protein binding	GIGYF2	IPI	UniProtKB:Q13322	Human	PMID:20670374
Molecular Function	GO:0005515	protein binding	GIGYF2	IPI	UniProtKB:O94979	Human	PMID:20696395
Molecular Function	GO:0005515	protein binding	GIGYF2	IPI	UniProtKB:P11940	Human	PMID:20696395
Molecular Function	GO:0005515	protein binding	GIGYF2	IPI	UniProtKB:P26368	Human	PMID:20696395
Molecular Function	GO:0005515	protein binding	GIGYF2	IPI	UniProtKB:P54259	Human	PMID:20696395
Molecular Function	GO:0005515	protein binding	GIGYF2	IPI	UniProtKB:P55735	Human	PMID:20696395
Molecular Function	GO:0005515	protein binding	GIGYF2	IPI	UniProtKB:Q01081	Human	PMID:20696395
Molecular Function	GO:0005515	protein binding	GIGYF2	IPI	UniProtKB:Q14444	Human	PMID:20696395
Molecular Function	GO:0005515	protein binding	GIGYF2	IPI	UniProtKB:Q16637	Human	PMID:20696395
Molecular Function	GO:0005515	protein binding	GIGYF2	IPI	UniProtKB:Q6P2Q9	Human	PMID:20696395
Molecular Function	GO:0005515	protein binding	GIGYF2	IPI	UniProtKB:Q9Y4Z0	Human	PMID:20696395
Molecular Function	GO:0005515	protein binding	GIGYF2	IPI	UniProtKB:O75420,UniProtKB:P00533,UniProtKB:P31749,UniProtKB:Q13322,UniProtKB:Q92600	Human	PMID:20878056
Molecular Function	GO:0005515	protein binding	GIGYF2	IPI	UniProtKB:Q13322,UniProtKB:Q92600	Human	PMID:20878056
Molecular Function	GO:0005515	protein binding	GIGYF2	IPI	UniProtKB:Q92600	Human	PMID:20878056
Molecular Function	GO:0005515	protein binding	GIGYF2	IPI	UniProtKB:Q9UKV8	Human	PMID:27157137
Molecular Function	GO:0005515	protein binding	GIGYF2	IPI	UniProtKB:O60573-1	Human	PMID:28698298
Molecular Function	GO:0005515	protein binding	GIGYF2	IPI	UniProtKB:O60573	Human	PMID:31439631
Molecular Function	GO:0005515	protein binding	GIGYF2	IPI	UniProtKB:P26196	Human	PMID:31439631
Molecular Function	GO:0005515	protein binding	GIGYF2	IPI	UniProtKB:P26651	Human	PMID:31439631
Molecular Function	GO:0005515	protein binding	Gigyf2	IPI	PR:Q60760	Mouse	PMID:12771153
Molecular Function	GO:0003723	RNA binding	GIGYF2	HDA		Human	PMID:22681889
Cellular Component	GO:0005737	cytoplasm	Gigyf2	IDA		Mouse	MGI:MGI:5816447|PMID:20670374
Cellular Component	GO:0010494	cytoplasmic stress granule	GIGYF2	IDA		Human	PMID:20696395
Cellular Component	GO:0005829	cytosol	GIGYF2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005783	endoplasmic reticulum	GIGYF2	IDA		Human	PMID:20696395
Cellular Component	GO:0005768	endosome	GIGYF2	IDA		Human	PMID:20670374
Cellular Component	GO:0005794	Golgi apparatus	GIGYF2	IDA		Human	PMID:20696395
Cellular Component	GO:0016020	membrane	GIGYF2	HDA		Human	PMID:19946888
Cellular Component	GO:0016020	membrane	Gigyf2	IDA		Mouse	MGI:MGI:5816447|PMID:20670374
Cellular Component	GO:0043204	perikaryon	GIGYF2	IDA		Human	PMID:20670374
Cellular Component	GO:0043204	perikaryon	Gigyf2	IDA		Mouse	MGI:MGI:5816447|PMID:20670374
Cellular Component	GO:0032991	protein-containing complex	GIGYF2	IDA		Human	PMID:20878056
Cellular Component	GO:1990635	proximal dendrite	GIGYF2	IDA		Human	PMID:20670374
Cellular Component	GO:1990635	proximal dendrite	Gigyf2	IDA		Mouse	MGI:MGI:5816447|PMID:20670374
Cellular Component	GO:0031982	vesicle	Gigyf2	IDA		Mouse	MGI:MGI:5816447|PMID:20670374
Biological Process	GO:0008344	adult locomotory behavior	Gigyf2	IMP	MGI:MGI:4126459	Mouse	PMID:19744960
Biological Process	GO:0007631	feeding behavior	Gigyf2	IMP	MGI:MGI:4126459	Mouse	PMID:19744960
Biological Process	GO:0048873	homeostasis of number of cells within a tissue	Gigyf2	IMP	MGI:MGI:4126459	Mouse	PMID:19744960
Biological Process	GO:0048009	insulin-like growth factor receptor signaling pathway	GIGYF2	IMP		Human	PMID:20670374
Biological Process	GO:0048009	insulin-like growth factor receptor signaling pathway	Gigyf2	IMP	MGI:MGI:4126459	Mouse	PMID:19744960
Biological Process	GO:0031571	mitotic G1 DNA damage checkpoint signaling	Gigyf2	IMP	MGI:MGI:4126459	Mouse	PMID:19744960
Biological Process	GO:0061157	mRNA destabilization	GIGYF2	IDA		Human	PMID:27157137
Biological Process	GO:0035264	multicellular organism growth	Gigyf2	IMP	MGI:MGI:4126459	Mouse	PMID:19744960
Biological Process	GO:0050881	musculoskeletal movement	Gigyf2	IMP	MGI:MGI:4126459	Mouse	PMID:19744960
Biological Process	GO:0017148	negative regulation of translation	GIGYF2	IMP		Human	PMID:22751931
Biological Process	GO:0050885	neuromuscular process controlling balance	Gigyf2	IMP	MGI:MGI:4126459	Mouse	PMID:19744960
Biological Process	GO:0009791	post-embryonic development	Gigyf2	IMP	MGI:MGI:4126459	Mouse	PMID:19744960
Biological Process	GO:0016441	post-transcriptional gene silencing	GIGYF2	IDA		Human	PMID:27157137
Biological Process	GO:0019538	protein metabolic process	Gigyf2	IMP	MGI:MGI:4126459	Mouse	PMID:19744960
Biological Process	GO:0021522	spinal cord motor neuron differentiation	Gigyf2	IMP	MGI:MGI:4126459	Mouse	PMID:19744960

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern