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Term Detail
GO term:protein metabolic process
Synonym: protein metabolic process and modification
Synonym: protein metabolism
Synonym: protein metabolism and modification
GO id:GO:0019538
Alternate id: GO:0006411
Definition:The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.
Number of paths to term: 4

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-anitrogen compound metabolic process
                                is-aorganonitrogen compound metabolic process
                                        is-a2-chloro-N-isopropylacetanilide metabolic process +
                                        is-a3-methylquinoline metabolic process +
                                        is-a7,8-didemethyl-8-hydroxy-5-deazariboflavin metabolic process +
                                        is-aalkaloid metabolic process +
                                        is-aallantoin metabolic process +
                                        is-aalpha-ribazole metabolic process +
                                        is-aamine metabolic process +
                                        is-aamino-acid betaine metabolic process +
                                        is-aaminoglycan metabolic process +
                                        is-aaminophosphonate metabolic process
                                        is-aansamycin metabolic process +
                                        is-abiotin metabolic process +
                                        is-acaprolactam metabolic process +
                                        is-acarbazole metabolic process +
                                        is-acatecholamine metabolic process +
                                        is-acellular amino acid metabolic process +
                                        is-acellular modified amino acid metabolic process +
                                        is-aclavulanic acid metabolic process +
                                        is-acoenzyme gamma-F420-2 metabolic process +
                                        is-acreatinine metabolic process +
                                        is-acyanate metabolic process +
                                        is-adethiobiotin metabolic process +
                                        is-adihydrolipoamide metabolic process
                                        is-adipyrrin metabolic process +
                                        is-aectoine metabolic process +
                                        is-aepothilone metabolic process +
                                        is-aF420-0 metabolic process
                                        is-aflavin-containing compound metabolic process +
                                        is-aformamide metabolic process +
                                        is-aglutathione derivative metabolic process +
                                        is-aglycosinolate metabolic process +
                                        is-aimidazole-containing compound metabolic process +
                                        is-aindole-containing compound metabolic process +
                                        is-akynurenic acid metabolic process +
                                        is-alipoamide metabolic process
                                        is-amethanophenazine metabolic process +
                                        is-amitomycin C metabolic process +
                                        is-amolybdopterin cofactor metabolic process +
                                        is-aN',N'',N'''-triacetylfusarinine C metabolic process +
                                        is-aN-acylphosphatidylethanolamine metabolic process
                                        is-anitrile metabolic process +
                                        is-anitrilotriacetate metabolic process +
                                        is-anovobiocin metabolic process +
                                        is-anucleobase metabolic process +
                                        is-anucleoside metabolic process +
                                        is-aorganonitrogen compound biosynthetic process +
                                        is-aorganonitrogen compound catabolic process +
                                        is-apeptide metabolic process +
                                        is-aphosphatidylcholine metabolic process +
                                        is-aplatelet activating factor metabolic process +
                                        is-aprimary amino compound metabolic process +
                                        is-aprotein metabolic process [GO:0019538] (5055 genes, 12371 annotations)
                                                is-aacyl-carrier-protein biosynthetic process +
                                                is-aamyloid fibril formation +
                                                is-aamyloid precursor protein metabolic process +
                                                is-acellular protein metabolic process +
                                                is-acytochrome metabolic process +
                                                is-acytokine metabolic process +
                                                is-aglycoprotein metabolic process +
                                                is-ahemoglobin metabolic process +
                                                is-ainsulin metabolic process +
                                                is-alipoprotein metabolic process +
                                                is-alow-density lipoprotein particle receptor biosynthetic process +
                                                is-ametabolism by organism of protein in other organism involved in symbiotic interaction +
                                                is-aMo-molybdopterin cofactor biosynthetic process +
                                                is-amulticellular organismal protein metabolic process +
                                                negatively-regulatesnegative regulation of protein metabolic process +
                                                positively-regulatespositive regulation of protein metabolic process +
                                                is-aprotein activation cascade +
                                                is-aprotein catabolic process +
                                                is-aprotein maturation +
                                                is-aprotein modification process +
                                                is-aproteolysis +
                                                regulatesregulation of protein metabolic process +
                                                is-athymidylate synthase biosynthetic process +
                                                is-aTRAIL receptor 1 biosynthetic process +
                                                is-aTRAIL receptor 2 biosynthetic process +
                                                is-aW-molybdopterin cofactor biosynthetic process
                                        is-apseurotin A metabolic process +
                                        is-apteridine-containing compound metabolic process +
                                        is-apurine-containing compound metabolic process +
                                        is-apyochelin metabolic process +
                                        is-apyridine-containing compound metabolic process +
                                        is-apyrimidine-containing compound metabolic process +
                                        is-arhizobactin 1021 metabolic process +
                                        is-as-triazine compound metabolic process +
                                        is-asphingolipid metabolic process +
                                        is-ataurine metabolic process +
                                        is-atetrapyrrole metabolic process +
                                        is-athermospermine metabolic process +
                                        is-athiazole metabolic process +
                                        is-atrimethylenediamine metabolic process +
                                        is-aurea metabolic process +
                                        is-avibriobactin metabolic process +
                                        is-awybutosine metabolic process +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-aaminoglycan metabolic process +
                                        is-aamylopectin metabolic process +
                                        is-aATP generation from poly-ADP-D-ribose
                                        is-acellular macromolecule metabolic process +
                                        is-acyanophycin metabolic process
                                        is-agene expression +
                                        is-amacromolecule biosynthetic process +
                                        is-amacromolecule catabolic process +
                                        is-amacromolecule modification +
                                        is-ametabolism of macromolecule in other organism involved in symbiotic interaction +
                                        is-amulticellular organismal macromolecule metabolic process +
                                        negatively-regulatesnegative regulation of macromolecule metabolic process +
                                        is-anucleic acid metabolic process +
                                        is-apolynucleotide dephosphorylation +
                                        is-apolysaccharide metabolic process +
                                        positively-regulatespositive regulation of macromolecule metabolic process +
                                        is-aprotein metabolic process [GO:0019538] (5055 genes, 12371 annotations)
                                                is-aacyl-carrier-protein biosynthetic process +
                                                is-aamyloid fibril formation +
                                                is-aamyloid precursor protein metabolic process +
                                                is-acellular protein metabolic process +
                                                is-acytochrome metabolic process +
                                                is-acytokine metabolic process +
                                                is-aglycoprotein metabolic process +
                                                is-ahemoglobin metabolic process +
                                                is-ainsulin metabolic process +
                                                is-alipoprotein metabolic process +
                                                is-alow-density lipoprotein particle receptor biosynthetic process +
                                                is-ametabolism by organism of protein in other organism involved in symbiotic interaction +
                                                is-aMo-molybdopterin cofactor biosynthetic process +
                                                is-amulticellular organismal protein metabolic process +
                                                negatively-regulatesnegative regulation of protein metabolic process +
                                                positively-regulatespositive regulation of protein metabolic process +
                                                is-aprotein activation cascade +
                                                is-aprotein catabolic process +
                                                is-aprotein maturation +
                                                is-aprotein modification process +
                                                is-aproteolysis +
                                                regulatesregulation of protein metabolic process +
                                                is-athymidylate synthase biosynthetic process +
                                                is-aTRAIL receptor 1 biosynthetic process +
                                                is-aTRAIL receptor 2 biosynthetic process +
                                                is-aW-molybdopterin cofactor biosynthetic process
                                        regulatesregulation of macromolecule metabolic process +
                                        is-ateichoic acid metabolic process +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-aorganonitrogen compound metabolic process
                                        is-a2-chloro-N-isopropylacetanilide metabolic process +
                                        is-a3-methylquinoline metabolic process +
                                        is-a7,8-didemethyl-8-hydroxy-5-deazariboflavin metabolic process +
                                        is-aalkaloid metabolic process +
                                        is-aallantoin metabolic process +
                                        is-aalpha-ribazole metabolic process +
                                        is-aamine metabolic process +
                                        is-aamino-acid betaine metabolic process +
                                        is-aaminoglycan metabolic process +
                                        is-aaminophosphonate metabolic process
                                        is-aansamycin metabolic process +
                                        is-abiotin metabolic process +
                                        is-acaprolactam metabolic process +
                                        is-acarbazole metabolic process +
                                        is-acatecholamine metabolic process +
                                        is-acellular amino acid metabolic process +
                                        is-acellular modified amino acid metabolic process +
                                        is-aclavulanic acid metabolic process +
                                        is-acoenzyme gamma-F420-2 metabolic process +
                                        is-acreatinine metabolic process +
                                        is-acyanate metabolic process +
                                        is-adethiobiotin metabolic process +
                                        is-adihydrolipoamide metabolic process
                                        is-adipyrrin metabolic process +
                                        is-aectoine metabolic process +
                                        is-aepothilone metabolic process +
                                        is-aF420-0 metabolic process
                                        is-aflavin-containing compound metabolic process +
                                        is-aformamide metabolic process +
                                        is-aglutathione derivative metabolic process +
                                        is-aglycosinolate metabolic process +
                                        is-aimidazole-containing compound metabolic process +
                                        is-aindole-containing compound metabolic process +
                                        is-akynurenic acid metabolic process +
                                        is-alipoamide metabolic process
                                        is-amethanophenazine metabolic process +
                                        is-amitomycin C metabolic process +
                                        is-amolybdopterin cofactor metabolic process +
                                        is-aN',N'',N'''-triacetylfusarinine C metabolic process +
                                        is-aN-acylphosphatidylethanolamine metabolic process
                                        is-anitrile metabolic process +
                                        is-anitrilotriacetate metabolic process +
                                        is-anovobiocin metabolic process +
                                        is-anucleobase metabolic process +
                                        is-anucleoside metabolic process +
                                        is-aorganonitrogen compound biosynthetic process +
                                        is-aorganonitrogen compound catabolic process +
                                        is-apeptide metabolic process +
                                        is-aphosphatidylcholine metabolic process +
                                        is-aplatelet activating factor metabolic process +
                                        is-aprimary amino compound metabolic process +
                                        is-aprotein metabolic process [GO:0019538] (5055 genes, 12371 annotations)
                                                is-aacyl-carrier-protein biosynthetic process +
                                                is-aamyloid fibril formation +
                                                is-aamyloid precursor protein metabolic process +
                                                is-acellular protein metabolic process +
                                                is-acytochrome metabolic process +
                                                is-acytokine metabolic process +
                                                is-aglycoprotein metabolic process +
                                                is-ahemoglobin metabolic process +
                                                is-ainsulin metabolic process +
                                                is-alipoprotein metabolic process +
                                                is-alow-density lipoprotein particle receptor biosynthetic process +
                                                is-ametabolism by organism of protein in other organism involved in symbiotic interaction +
                                                is-aMo-molybdopterin cofactor biosynthetic process +
                                                is-amulticellular organismal protein metabolic process +
                                                negatively-regulatesnegative regulation of protein metabolic process +
                                                positively-regulatespositive regulation of protein metabolic process +
                                                is-aprotein activation cascade +
                                                is-aprotein catabolic process +
                                                is-aprotein maturation +
                                                is-aprotein modification process +
                                                is-aproteolysis +
                                                regulatesregulation of protein metabolic process +
                                                is-athymidylate synthase biosynthetic process +
                                                is-aTRAIL receptor 1 biosynthetic process +
                                                is-aTRAIL receptor 2 biosynthetic process +
                                                is-aW-molybdopterin cofactor biosynthetic process
                                        is-apseurotin A metabolic process +
                                        is-apteridine-containing compound metabolic process +
                                        is-apurine-containing compound metabolic process +
                                        is-apyochelin metabolic process +
                                        is-apyridine-containing compound metabolic process +
                                        is-apyrimidine-containing compound metabolic process +
                                        is-arhizobactin 1021 metabolic process +
                                        is-as-triazine compound metabolic process +
                                        is-asphingolipid metabolic process +
                                        is-ataurine metabolic process +
                                        is-atetrapyrrole metabolic process +
                                        is-athermospermine metabolic process +
                                        is-athiazole metabolic process +
                                        is-atrimethylenediamine metabolic process +
                                        is-aurea metabolic process +
                                        is-avibriobactin metabolic process +
                                        is-awybutosine metabolic process +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aprimary metabolic process
                                is-acarbohydrate metabolic process +
                                is-acellular amino acid metabolic process +
                                is-alipid metabolic process +
                                is-anucleobase-containing compound metabolic process +
                                is-aprotein metabolic process [GO:0019538] (5055 genes, 12371 annotations)
                                        is-aacyl-carrier-protein biosynthetic process +
                                        is-aamyloid fibril formation +
                                        is-aamyloid precursor protein metabolic process +
                                        is-acellular protein metabolic process +
                                        is-acytochrome metabolic process +
                                        is-acytokine metabolic process +
                                        is-aglycoprotein metabolic process +
                                        is-ahemoglobin metabolic process +
                                        is-ainsulin metabolic process +
                                        is-alipoprotein metabolic process +
                                        is-alow-density lipoprotein particle receptor biosynthetic process +
                                        is-ametabolism by organism of protein in other organism involved in symbiotic interaction +
                                        is-aMo-molybdopterin cofactor biosynthetic process +
                                        is-amulticellular organismal protein metabolic process +
                                        negatively-regulatesnegative regulation of protein metabolic process +
                                        positively-regulatespositive regulation of protein metabolic process +
                                        is-aprotein activation cascade +
                                        is-aprotein catabolic process +
                                        is-aprotein maturation +
                                        is-aprotein modification process +
                                        is-aproteolysis +
                                        regulatesregulation of protein metabolic process +
                                        is-athymidylate synthase biosynthetic process +
                                        is-aTRAIL receptor 1 biosynthetic process +
                                        is-aTRAIL receptor 2 biosynthetic process +
                                        is-aW-molybdopterin cofactor biosynthetic process
                                regulatesregulation of primary metabolic process +
                                is-atricarboxylic acid cycle +


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last database update
04/18/2017
MGI 6.08
The Jackson Laboratory