Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GFI1B
  • Mouse genes Gfi1b
  • Rat genes Gfi1b
  • Zfish genes gfi1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gfi1b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	GFI1B	IPI	UniProtKB:Q06455	Human	PMID:12874834
Molecular Function	GO:0005515	protein binding	GFI1B	IPI	UniProtKB:Q99435	Human	PMID:16713569
Molecular Function	GO:0005515	protein binding	GFI1B	IPI	UniProtKB:Q9HC77	Human	PMID:16713569
Molecular Function	GO:0005515	protein binding	GFI1B	IPI	UniProtKB:Q9Y219	Human	PMID:16713569
Molecular Function	GO:0005515	protein binding	Gfi1b	IPI	UniProtKB:O54864|UniProtKB:Q9Z148	Mouse	MGI:MGI:3629243|PMID:16688220
Molecular Function	GO:0005515	protein binding	Gfi1b	IPI	PR:Q6PGA0	Mouse	PMID:24843136
Molecular Function	GO:0005515	protein binding	Gfi1b	IPI	PR:Q8C796	Mouse	PMID:24843136
Molecular Function	GO:0005515	protein binding	Gfi1b	IPI	PR:P23611	Mouse	PMID:25331958
Molecular Function	GO:0005515	protein binding	Gfi1b	IPI	PR:Q8CFE3	Mouse	PMID:24843136
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	GFI1B	IPI	UniProtKB:Q8IX07	Human	PMID:15920471
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	GFI1B	IDA		Human	PMID:28473536
Cellular Component	GO:0016363	nuclear matrix	GFI1B	IDA		Human	PMID:12874834
Cellular Component	GO:0005654	nucleoplasm	GFI1B	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	GFI1B	IDA		Human	PMID:12874834
Cellular Component	GO:0005886	plasma membrane	GFI1B	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005667	transcription regulator complex	GFI1B	IDA		Human	PMID:15920471
Biological Process	GO:0060216	definitive hemopoiesis	gfi1b	IGI	ZFIN:ZDB-GENO-091020-2	Zfish	PMID:22960038
Biological Process	GO:0060216	definitive hemopoiesis	gfi1b	IMP	ZFIN:ZDB-MRPHLNO-130222-5	Zfish	PMID:22960038
Biological Process	GO:0060216	definitive hemopoiesis	gfi1b	IMP	ZFIN:ZDB-MRPHLNO-130222-4	Zfish	PMID:22960038
Biological Process	GO:0030218	erythrocyte differentiation	gfi1b	IMP	ZFIN:ZDB-MRPHLNO-130222-4	Zfish	PMID:22960038
Biological Process	GO:0030099	myeloid cell differentiation	gfi1b	IMP	ZFIN:ZDB-MRPHLNO-130304-4	Zfish	PMID:23122293
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	GFI1B	IDA		Human	PMID:9566867
Biological Process	GO:0030854	positive regulation of granulocyte differentiation	Gfi1b	IDA		Mouse	MGI:MGI:5284774|PMID:17707228
Biological Process	GO:0045646	regulation of erythrocyte differentiation	Gfi1b	IMP		Mouse	MGI:MGI:5284774|PMID:17707228

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern