Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GDF7
  • Mouse genes Gdf7
  • Rat genes Gdf7
  • Zfish genes gdf7
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gdf7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	Gdf7	IPI	PR:P43029	Mouse	PMID:16049014
Molecular Function	GO:0005515	protein binding	GDF7	IPI	UniProtKB:P37023	Human	PMID:16049014
Molecular Function	GO:0005515	protein binding	Gdf7	IPI	PR:P23359	Mouse	PMID:12741987
Cellular Component	GO:0005576	extracellular region	Gdf7	IDA		Mouse	PMID:12741987
Biological Process	GO:0032924	activin receptor signaling pathway	GDF7	IDA		Human	PMID:16049014
Biological Process	GO:0007411	axon guidance	Gdf7	IDA		Mouse	PMID:12639970
Biological Process	GO:0030509	BMP signaling pathway	GDF7	IDA		Human	PMID:16049014
Biological Process	GO:0030509	BMP signaling pathway	Gdf7	IDA		Mouse	PMID:16049014
Biological Process	GO:0030509	BMP signaling pathway	Gdf7	IGI	MGI:MGI:1338938	Mouse	PMID:16049014
Biological Process	GO:0030509	BMP signaling pathway	Gdf7	IGI	MGI:MGI:107191	Mouse	PMID:16049014
Biological Process	GO:0048754	branching morphogenesis of an epithelial tube	Gdf7	IMP	MGI:MGI:2387817	Mouse	PMID:11356025
Biological Process	GO:0045165	cell fate commitment	Gdf7	IDA		Mouse	PMID:15883363
Biological Process	GO:0030855	epithelial cell differentiation	Gdf7	IMP	MGI:MGI:2387817	Mouse	PMID:11356025
Biological Process	GO:0048853	forebrain morphogenesis	Gdf7	IMP	MGI:MGI:2386906	Mouse	PMID:10693795
Biological Process	GO:0022612	gland morphogenesis	Gdf7	IMP	MGI:MGI:2387817	Mouse	PMID:11356025
Biological Process	GO:0030901	midbrain development	Gdf7	IMP	MGI:MGI:2386906	Mouse	PMID:10693795
Biological Process	GO:0060571	morphogenesis of an epithelial fold	Gdf7	IMP	MGI:MGI:2387817	Mouse	PMID:11356025
Biological Process	GO:0021915	neural tube development	Gdf7	IMP	MGI:MGI:2386906	Mouse	PMID:10693795
Biological Process	GO:0060389	pathway-restricted SMAD protein phosphorylation	GDF7	IDA		Human	PMID:16049014
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	GDF7	IDA		Human	PMID:16049014
Biological Process	GO:0010628	positive regulation of gene expression	Gdf7	IDA		Mouse	MGI:MGI:5294519|PMID:21412429
Biological Process	GO:0045666	positive regulation of neuron differentiation	Gdf7	IDA		Mouse	PMID:9786991
Biological Process	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	GDF7	IDA		Human	PMID:16049014
Biological Process	GO:2001051	positive regulation of tendon cell differentiation	Gdf7	IDA		Mouse	MGI:MGI:5294519|PMID:21412429
Biological Process	GO:0048608	reproductive structure development	Gdf7	IMP	MGI:MGI:2387817	Mouse	PMID:11356021
Biological Process	GO:0021509	roof plate formation	Gdf7	IMP	MGI:MGI:2386906	Mouse	PMID:10693795
Biological Process	GO:0021527	spinal cord association neuron differentiation	Gdf7	IMP	MGI:MGI:2386906	Mouse	PMID:10693795

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern