Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GAD2
  • Mouse genes Gad2
  • Rat genes Gad2
  • Zfish genes gad2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gad2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016595	glutamate binding	Gad2	IDA		Rat	PMID:10812196|RGD:6480261
Molecular Function	GO:0004351	glutamate decarboxylase activity	Gad2	IDA		Rat	PMID:10812196|RGD:6480261
Molecular Function	GO:0004351	glutamate decarboxylase activity	Gad2	IDA		Rat	PMID:8999827|RGD:1625237
Molecular Function	GO:0005515	protein binding	GAD2	IPI	UniProtKB:Q99259	Human	PMID:10671565
Molecular Function	GO:0005515	protein binding	GAD2	IPI	UniProtKB:Q15041	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GAD2	IPI	UniProtKB:Q6RW13	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GAD2	IPI	UniProtKB:Q969L2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GAD2	IPI	UniProtKB:Q96B96	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GAD2	IPI	UniProtKB:Q96DZ9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GAD2	IPI	UniProtKB:A0PK00	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GAD2	IPI	UniProtKB:A8MV81	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GAD2	IPI	UniProtKB:O15126	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GAD2	IPI	UniProtKB:O43761	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GAD2	IPI	UniProtKB:O60664	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GAD2	IPI	UniProtKB:O60906	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GAD2	IPI	UniProtKB:P55056	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GAD2	IPI	UniProtKB:Q06432	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GAD2	IPI	UniProtKB:Q15041	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GAD2	IPI	UniProtKB:Q3SXY8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GAD2	IPI	UniProtKB:Q5BJH2-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GAD2	IPI	UniProtKB:Q5EB52	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GAD2	IPI	UniProtKB:Q5T9G4-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GAD2	IPI	UniProtKB:Q6E0U4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GAD2	IPI	UniProtKB:Q6PIF2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GAD2	IPI	UniProtKB:Q6RW13-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GAD2	IPI	UniProtKB:Q6ZPD8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GAD2	IPI	UniProtKB:Q6ZWK4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GAD2	IPI	UniProtKB:Q7Z7G2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GAD2	IPI	UniProtKB:Q86UF1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GAD2	IPI	UniProtKB:Q8IZV5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GAD2	IPI	UniProtKB:Q8N3Y7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GAD2	IPI	UniProtKB:Q8N8Q1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GAD2	IPI	UniProtKB:Q8N9I5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GAD2	IPI	UniProtKB:Q8WTS1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GAD2	IPI	UniProtKB:Q8WZ55	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GAD2	IPI	UniProtKB:Q969L2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GAD2	IPI	UniProtKB:Q96AL5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GAD2	IPI	UniProtKB:Q96B96	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GAD2	IPI	UniProtKB:Q96DZ9-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GAD2	IPI	UniProtKB:Q96GL9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GAD2	IPI	UniProtKB:Q96IW7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GAD2	IPI	UniProtKB:Q96Q80	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GAD2	IPI	UniProtKB:Q9BUN8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GAD2	IPI	UniProtKB:Q9H400	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GAD2	IPI	UniProtKB:Q9HC36	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GAD2	IPI	UniProtKB:Q9NRY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GAD2	IPI	UniProtKB:Q9NS64	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GAD2	IPI	UniProtKB:Q9NZD8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GAD2	IPI	UniProtKB:Q9UBN6	Human	PMID:32296183
Molecular Function	GO:0044877	protein-containing complex binding	Gad2	IDA		Rat	PMID:7836456|RGD:6480262
Molecular Function	GO:0030170	pyridoxal phosphate binding	Gad2	IDA		Rat	PMID:1880546|RGD:6480263
Cellular Component	GO:0030424	axon	Gad2	IDA		Mouse	PMID:15479642
Cellular Component	GO:0005737	cytoplasm	Gad2	IDA		Mouse	PMID:23500099
Cellular Component	GO:0031410	cytoplasmic vesicle	Gad2	IDA		Rat	PMID:8132714|RGD:1625236
Cellular Component	GO:0005829	cytosol	Gad2	IDA		Rat	PMID:17600303|RGD:6480260
Cellular Component	GO:0098982	GABA-ergic synapse	Gad2	IDA		Rat	PMID:15844209|RGD:1642495
Cellular Component	GO:0060077	inhibitory synapse	Gad2	IDA		Rat	PMID:21119615|RGD:8554416
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Gad2	IDA		Rat	PMID:8132714|RGD:1625236
Cellular Component	GO:0098793	presynapse	Gad2	IDA		Rat	PMID:15844209|RGD:1642495
Cellular Component	GO:0045202	synapse	Gad2	IDA		Mouse	PMID:15479642
Cellular Component	GO:0030672	synaptic vesicle membrane	Gad2	IDA		Rat	PMID:8999827|RGD:1625237
Biological Process	GO:0009449	gamma-aminobutyric acid biosynthetic process	gad2	IEP		Zfish	PMID:9634146
Biological Process	GO:0006540	glutamate decarboxylation to succinate	Gad2	IDA		Rat	PMID:8999827|RGD:1625237
Biological Process	GO:0042136	neurotransmitter biosynthetic process	Gad2	IDA		Rat	PMID:8336154|RGD:155230743
Biological Process	GO:0042136	neurotransmitter biosynthetic process	Gad2	IMP		Rat	PMID:8336154|RGD:155230743
Biological Process	GO:0042136	neurotransmitter biosynthetic process	gad2	IEP		Zfish	PMID:9634146
Biological Process	GO:0009410	response to xenobiotic stimulus	Gad2	IEP		Rat	PMID:19359144|RGD:2317787

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern