Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GABRD
  • Mouse genes Gabrd
  • Rat genes Gabrd
  • Zfish genes gabrd
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gabrd

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004890	GABA-A receptor activity	Gabrd	IDA		Rat	PMID:12356876|RGD:727440
Molecular Function	GO:0005515	protein binding	GABRD	IPI	UniProtKB:Q9UMX0	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	GABRD	IPI	UniProtKB:Q7Z3S9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GABRD	IPI	UniProtKB:Q9UMX0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GABRD	IPI	UniProtKB:Q9UMX0-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GABRD	IPI	UniProtKB:Q99750	Human	PMID:32296183
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	Gabrd	IMP		Mouse	PMID:14627650
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	Gabrd	IDA		Mouse	PMID:14627650
Cellular Component	GO:0030424	axon	Gabrd	IDA		Mouse	MGI:MGI:6378137|PMID:25339733
Cellular Component	GO:0030425	dendrite	Gabrd	IDA		Mouse	MGI:MGI:6378137|PMID:25339733
Cellular Component	GO:0098982	GABA-ergic synapse	Gabrd	IDA		Mouse	PMID:14627650
Cellular Component	GO:0098982	GABA-ergic synapse	Gabrd	IMP		Mouse	PMID:14627650
Cellular Component	GO:0098982	GABA-ergic synapse	Gabrd	IDA		Rat	PMID:16467523|RGD:13702414
Cellular Component	GO:0098978	glutamatergic synapse	Gabrd	IDA		Rat	PMID:22213233|RGD:13702276
Cellular Component	GO:0043025	neuronal cell body	Gabrd	IDA		Mouse	MGI:MGI:6378137|PMID:25339733
Cellular Component	GO:0045211	postsynaptic membrane	Gabrd	IDA		Mouse	PMID:14627650
Cellular Component	GO:0045211	postsynaptic membrane	Gabrd	IDA		Rat	PMID:16467523|RGD:13702414
Cellular Component	GO:0045211	postsynaptic membrane	Gabrd	IDA		Rat	PMID:22213233|RGD:13702276
Biological Process	GO:0007268	chemical synaptic transmission	Gabrd	IDA		Rat	PMID:12356876|RGD:727440

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern