Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GABPA
  • Mouse genes Gabpa
  • Rat genes Gabpa
  • Zfish genes gabpa
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gabpa

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Gabpa	IDA		Mouse	PMID:22780989
Molecular Function	GO:0003682	chromatin binding	Gabpa	IDA		Mouse	PMID:16757682
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	GABPA	IDA		Human	PMID:12750007
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	GABPA	IDA		Human	PMID:22306510
Molecular Function	GO:0005515	protein binding	GABPA	IPI	UniProtKB:P51610	Human	PMID:10675337
Molecular Function	GO:0005515	protein binding	GABPA	IPI	UniProtKB:Q86XA0	Human	PMID:24501276
Molecular Function	GO:0005515	protein binding	GABPA	IPI	UniProtKB:Q8TAK5	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	GABPA	IPI	UniProtKB:O75716	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GABPA	IPI	UniProtKB:Q06547	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GABPA	IPI	UniProtKB:Q5TFG8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GABPA	IPI	UniProtKB:Q8TAK5	Human	PMID:32296183
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	GABPA	IDA		Human	PMID:12750007
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	GABPA	IDA		Human	PMID:22306510
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Gabpa	IDA		Mouse	PMID:11004506
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Gabpa	IDA		Mouse	PMID:15361867
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	GABPA	IDA		Human	PMID:28473536
Molecular Function	GO:0000976	transcription cis-regulatory region binding	GABPA	IDA		Human	PMID:9857059
Cellular Component	GO:0000785	chromatin	GABPA	IDA		Human	PMID:22306510
Cellular Component	GO:0005654	nucleoplasm	GABPA	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	GABPA	IDA		Human	PMID:9857059
Cellular Component	GO:0005634	nucleus	Gabpa	IDA		Mouse	PMID:11004506
Cellular Component	GO:0005634	nucleus	Gabpa	IDA		Mouse	PMID:15361867
Biological Process	GO:0001825	blastocyst formation	Gabpa	IMP		Mouse	PMID:27869233
Biological Process	GO:1903351	cellular response to dopamine	GABPA	IMP		Human	PMID:24136195
Biological Process	GO:0001701	in utero embryonic development	Gabpa	IMP	MGI:MGI:3665313	Mouse	PMID:17485447
Biological Process	GO:0045653	negative regulation of megakaryocyte differentiation	Gabpa	IMP	MGI:MGI:3054951	Mouse	PMID:16757682
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Gabpa	IMP	MGI:MGI:2447635,MGI:MGI:3665312	Mouse	PMID:17485447
Biological Process	GO:0010628	positive regulation of gene expression	GABPA	IMP		Human	PMID:24136195
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	GABPA	IDA		Human	PMID:9857059
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	GABPA	IDA		Human	PMID:12750007
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	GABPA	IDA		Human	PMID:22306510
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	GABPA	IDA		Human	PMID:24501276
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Gabpa	IDA		Mouse	PMID:15361867

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern