Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Fuz

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes FUZ
- Mouse genes Fuz
- Rat genes Fuz
- Zfish genes fuz
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fuz

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	FUZ	IPI	UniProtKB:Q9BU20	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	FUZ	IPI	UniProtKB:Q9BU20	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Fuz	IPI	PR:Q8CE72	Mouse	PMID:27158779
Cellular Component	GO:0070062	extracellular exosome	FUZ	HDA		Human	PMID:19056867
Biological Process	GO:0009952	anterior/posterior pattern specification	Fuz	IMP	MGI:MGI:4346364	Mouse	PMID:19877275
Biological Process	GO:0035904	aorta development	Fuz	IMP		Mouse	PMID:25807483
Biological Process	GO:0003279	cardiac septum development	Fuz	IMP		Mouse	PMID:25807483
Biological Process	GO:0060271	cilium assembly	Fuz	IMP		Mouse	MGI:MGI:4438317\|PMID:19767740
Biological Process	GO:0060271	cilium assembly	Fuz	IMP		Mouse	MGI:MGI:5009776\|PMID:20962855
Biological Process	GO:0060271	cilium assembly	Fuz	IMP	MGI:MGI:4346364	Mouse	PMID:19877275
Biological Process	GO:0060976	coronary vasculature development	Fuz	IMP		Mouse	PMID:25807483
Biological Process	GO:0010172	embryonic body morphogenesis	Fuz	IMP		Mouse	MGI:MGI:5498583\|PMID:23806618
Biological Process	GO:0010172	embryonic body morphogenesis	Fuz	IMP		Mouse	MGI:MGI:4438317\|PMID:19767740
Biological Process	GO:0010172	embryonic body morphogenesis	Fuz	IMP		Mouse	MGI:MGI:5296432\|PMID:21935430
Biological Process	GO:0042733	embryonic digit morphogenesis	Fuz	IMP	MGI:MGI:4346364	Mouse	PMID:19877275
Biological Process	GO:0042733	embryonic digit morphogenesis	Fuz	IMP	MGI:MGI:3531090	Mouse	PMID:27158779
Biological Process	GO:0048702	embryonic neurocranium morphogenesis	Fuz	IMP	MGI:MGI:3531090	Mouse	PMID:27395007
Biological Process	GO:0048702	embryonic neurocranium morphogenesis	Fuz	IGI	MGI:MGI:99604	Mouse	PMID:27395007
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	Fuz	IMP		Mouse	MGI:MGI:4438317\|PMID:19767740
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	Fuz	IMP		Mouse	MGI:MGI:5296432\|PMID:21935430
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	Fuz	IMP		Mouse	MGI:MGI:5498583\|PMID:23806618
Biological Process	GO:0001736	establishment of planar polarity	Fuz	IMP		Mouse	MGI:MGI:4438317\|PMID:19767740
Biological Process	GO:0001942	hair follicle development	Fuz	IMP		Mouse	MGI:MGI:5009776\|PMID:20962855
Biological Process	GO:0120223	larynx morphogenesis	Fuz	IMP	MGI:MGI:3531090	Mouse	PMID:28177282
Biological Process	GO:0120223	larynx morphogenesis	Fuz	IGI	MGI:MGI:99604	Mouse	PMID:28177282
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	Fuz	IMP		Mouse	MGI:MGI:5296432\|PMID:21935430
Biological Process	GO:0030336	negative regulation of cell migration	FUZ	IMP		Human	PMID:21840926
Biological Process	GO:0008285	negative regulation of cell population proliferation	Fuz	IMP		Mouse	MGI:MGI:5296432\|PMID:21935430
Biological Process	GO:2000314	negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation	Fuz	IMP		Mouse	MGI:MGI:5498583\|PMID:23806618
Biological Process	GO:0090301	negative regulation of neural crest formation	Fuz	IMP		Mouse	MGI:MGI:5498583\|PMID:23806618
Biological Process	GO:0001843	neural tube closure	FUZ	IMP		Human	PMID:21840926
Biological Process	GO:0001843	neural tube closure	Fuz	IMP		Mouse	MGI:MGI:4438317\|PMID:19767740
Biological Process	GO:0001843	neural tube closure	Fuz	IMP		Mouse	MGI:MGI:5296277\|PMID:21840926
Biological Process	GO:0001843	neural tube closure	Fuz	IMP	MGI:MGI:4346364	Mouse	PMID:19877275
Biological Process	GO:1905515	non-motile cilium assembly	FUZ	IMP		Human	PMID:21840926
Biological Process	GO:1905515	non-motile cilium assembly	Fuz	IMP		Mouse	MGI:MGI:5296432\|PMID:21935430
Biological Process	GO:0045724	positive regulation of cilium assembly	FUZ	IMP		Human	PMID:21840926
Biological Process	GO:0045724	positive regulation of cilium assembly	Fuz	IMP		Mouse	MGI:MGI:5296432\|PMID:21935430
Biological Process	GO:0010954	positive regulation of protein processing	Fuz	IMP	MGI:MGI:4346364	Mouse	PMID:19877275
Biological Process	GO:0008589	regulation of smoothened signaling pathway	Fuz	IMP		Mouse	MGI:MGI:5296432\|PMID:21935430
Biological Process	GO:0008589	regulation of smoothened signaling pathway	Fuz	IMP		Mouse	MGI:MGI:4438317\|PMID:19767740
Biological Process	GO:0008589	regulation of smoothened signaling pathway	Fuz	IMP		Mouse	MGI:MGI:5009776\|PMID:20962855
Biological Process	GO:0008589	regulation of smoothened signaling pathway	Fuz	IMP		Mouse	MGI:MGI:5498583\|PMID:23806618
Biological Process	GO:0008589	regulation of smoothened signaling pathway	Fuz	IMP	MGI:MGI:4346364	Mouse	PMID:19877275
Biological Process	GO:0060021	roof of mouth development	Fuz	IMP	MGI:MGI:3531090	Mouse	PMID:27158779
Biological Process	GO:0021510	spinal cord development	Fuz	IMP	MGI:MGI:4346364	Mouse	PMID:19877275
Biological Process	GO:0021513	spinal cord dorsal/ventral patterning	Fuz	IMP	MGI:MGI:4346364	Mouse	PMID:21761479
Biological Process	GO:0043587	tongue morphogenesis	Fuz	IMP	MGI:MGI:3531090	Mouse	PMID:27158779

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/30/2025 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.