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Fuz
Gene Detail
 Symbol
Name
ID
Fuz
fuzzy homolog (Drosophila)
MGI:1917550
Synonyms 2600013E07Rik, b2b1273Clo
Feature Type protein coding gene
Genetic Map
Chromosome 7
28.99 cM, cytoband B2
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:44896079-44902631 bp, + strand
From VEGA annotation of GRCm38

  6553 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:11840  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 zebrafish

Gene Tree: Fuz

Human
homologs
Human Homolog FUZ, fuzzy planar cell polarity protein
NCBI Gene ID 80199
neXtProt AC  NX_Q9BT04
Human Synonyms  FY, NTD
Human Chr (Location)  19q13.33; chr19:49806866-49813814 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human FUZ
Alleles
and
phenotypes
All alleles(11) : Targeted(2) Gene trapped(8) Chemically induced(1)
 
Mice homozygous for a gene trapped allele exhibit neural tube closure defects, abnormal craniofacial morphology, abnormal skeletal morphology, polydactyly, anopthalmia, pulmonary hopyplasia, and cardiac outflow tract defects.
 
Phenotype Images(20)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process cell projection organization, cilium assembly, ...
Component cytoplasm, cytoskeleton, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (10)    Tissues (10)   
Theiler Stages: 13, 15
Assay TypeResults
RNA in situ 10
cDNA source data(9)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(10) cDNA(10)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000035380 (Evidence)
Ensembl Gene ModelENSMUSG00000011658 (Evidence)
Entrez Gene70300 (Evidence)
DFCITC1582808, TC1595065, TC1601189, TC1657474
NIA Mouse Gene IndexU008057
Consensus CDS ProjectCCDS52237.1
International Mouse Knockout Project StatusFuz
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035380 VEGA Gene Model | MGI Sequence Detail 6553 C57BL/6J ±  kb
transcript OTTMUST00000090450 VEGA | MGI Sequence Detail 1697 Not Applicable 
polypeptide OTTMUSP00000049627 VEGA | MGI Sequence Detail 415 Not Applicable 

For the selected sequences
All sequences(86) RefSeq(11) UniProt(10)
Polymorphisms SNPs within 2kb(87 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR026069 Fuzzy protein
Protein Ontology PR:000007708 protein fuzzy
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:198631 Tabler JM, et al., Fuz Mutant Mice Reveal Shared Mechanisms between Ciliopathies and FGF-Related Syndromes. Dev Cell. 2013 Jun 24;25(6):623-35
All references(39)
Other
accession IDs
MGI:5311357

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory