Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FRMD7
  • Mouse genes Frmd7
  • Rat genes Frmd7
  • Zfish genes frmd7
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Frmd7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	FRMD7	IPI	UniProtKB:P54105	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Frmd7	IPI	PR:Q99PT1	Mouse	PMID:23967341
Cellular Component	GO:0005829	cytosol	FRMD7	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005615	extracellular space	FRMD7	HDA		Human	PMID:22664934
Cellular Component	GO:0030426	growth cone	Frmd7	IDA		Mouse	MGI:MGI:4413514|PMID:19892780
Cellular Component	GO:0043005	neuron projection	Frmd7	IDA		Mouse	MGI:MGI:4413514|PMID:19892780
Cellular Component	GO:0043025	neuronal cell body	Frmd7	IDA		Mouse	MGI:MGI:4413514|PMID:19892780
Cellular Component	GO:0005654	nucleoplasm	FRMD7	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	FRMD7	IDA		Human	GO_REF:0000052
Biological Process	GO:0032091	negative regulation of protein binding	Frmd7	IDA		Mouse	PMID:23967341
Biological Process	GO:0051497	negative regulation of stress fiber assembly	Frmd7	IDA		Mouse	PMID:23967341
Biological Process	GO:0010592	positive regulation of lamellipodium assembly	Frmd7	IDA		Mouse	PMID:23967341
Biological Process	GO:0051057	positive regulation of small GTPase mediated signal transduction	Frmd7	IGI	MGI:MGI:97845	Mouse	PMID:23967341
Biological Process	GO:0010975	regulation of neuron projection development	Frmd7	IMP		Mouse	MGI:MGI:4413514|PMID:19892780

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern