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Frmd7 Gene Detail
Summary
  • Symbol
    Frmd7
  • Name
    FERM domain containing 7
  • Synonyms
    EG665849, LOC385354
  • Feature Type
    protein coding gene
  • IDs
    MGI:2686379
    NCBI Gene: 385354
  • Gene Overview
    MyGene.info: FRMD7
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:50895180-50942710 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome X, 27.82 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    141 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2686379
protein coding gene ChrX:50892645-50943619 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035709
protein coding gene ChrX:46040567-46090514 (-)
A/J MGP_AJ_G0035692
protein coding gene ChrX:45920058-45967926 (-)
AKR/J MGP_AKRJ_G0035612
protein coding gene ChrX:47177409-47234436 (-)
BALB/cJ MGP_BALBcJ_G0035678
protein coding gene ChrX:45511149-45562169 (-)
C3H/HeJ MGP_C3HHeJ_G0035382
protein coding gene ChrX:46314370-46362726 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036207
protein coding gene ChrX:47153567-47201172 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033059
protein coding gene ChrX:43485658-43531252 (-)
CAST/EiJ MGP_CASTEiJ_G0034673
protein coding gene ChrX:33767002-33816947 (-)
CBA/J MGP_CBAJ_G0035356
protein coding gene ChrX:48440001-48500049 (-)
DBA/2J MGP_DBA2J_G0035511
protein coding gene ChrX:45749044-45797548 (-)
FVB/NJ MGP_FVBNJ_G0035459
protein coding gene ChrX:45453674-45501184 (-)
LP/J MGP_LPJ_G0035598
protein coding gene ChrX:46385695-46436265 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035498
protein coding gene ChrX:49981668-50035703 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036225
protein coding gene ChrX:45943481-45995166 (-)
PWK/PhJ MGP_PWKPhJ_G0034372
protein coding gene ChrX:33287572-33336526 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034217
protein coding gene ChrX:34550580-34604453 (-)
WSB/EiJ MGP_WSBEiJ_G0034817
protein coding gene ChrX:45491920-45544524 (-)



Homology
more
  • Human Ortholog
    FRMD7, FERM domain containing 7
  • Vertebrate Orthologs
    10
  • Human Ortholog
    FRMD7, FERM domain containing 7
    Orthology source: HomoloGene, HGNC
  • Synonyms
    NYS, NYS1, XIPAN
  • Links
    NCBI Gene ID: 90167
    neXtProt AC: NX_Q6ZUT3
    UniProt: Q6ZUT3

  • Chr Location
    Xq26.2; chrX:132076986-132128022 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 18855
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: FRMD7
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000036131 Ensembl Gene Model | MGI Sequence Detail 47531 C57BL/6J ±  kb
    transcript ENSMUST00000060650 Ensembl | MGI Sequence Detail 2112 Not Applicable  
    polypeptide ENSMUSP00000057103 Ensembl | MGI Sequence Detail 703 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 4
      cDNA 3
      Primer pair 1

      Microarray probesets 1
    Other
    Accession IDs
    less
    MGI:3643612
    References
    more
    • Summaries
      All 23
      Developmental Gene Expression 2
      Gene Ontology 4
      Phenotypes 6
    • Earliest
      J:155331 Betts-Henderson J, et al., The nystagmus-associated FRMD7 gene regulates neuronal outgrowth and development. Hum Mol Genet. 2010 Jan 15;19(2):342-51
    • Latest
      J:244794 Hillier D, et al., Causal evidence for retina-dependent and -independent visual motion computations in mouse cortex. Nat Neurosci. 2017 Jul;20(7):960-968

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory