Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FOXJ2
  • Mouse genes Foxj2
  • Rat genes Foxj2
  • Zfish genes foxj2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Foxj2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	FOXJ2	IDA		Human	PMID:10777590
Molecular Function	GO:0042802	identical protein binding	FOXJ2	IPI	UniProtKB:Q9P0K8	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	FOXJ2	IPI	UniProtKB:Q9H6Z9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FOXJ2	IPI	UniProtKB:Q9H0L4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FOXJ2	IPI	UniProtKB:Q9H6Z9	Human	PMID:32296183
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	FOXJ2	IDA		Human	PMID:10777590
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	FOXJ2	IDA		Human	PMID:28473536
Cellular Component	GO:0001650	fibrillar center	FOXJ2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	FOXJ2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	FOXJ2	IDA		Human	PMID:24792364
Biological Process	GO:0007141	male meiosis I	Foxj2	IMP		Mouse	MGI:MGI:6507254|PMID:27316861
Biological Process	GO:0016525	negative regulation of angiogenesis	FOXJ2	IMP		Human	PMID:24792364
Biological Process	GO:0110059	negative regulation of blood vessel endothelial cell differentiation	FOXJ2	IDA		Human	PMID:24792364
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	FOXJ2	IDA		Human	PMID:10777590
Biological Process	GO:1904707	positive regulation of vascular associated smooth muscle cell proliferation	FOXJ2	IDA		Human	PMID:24792364
Biological Process	GO:0007283	spermatogenesis	Foxj2	IMP		Mouse	MGI:MGI:6507254|PMID:27316861

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern