Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Fnta

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes FNTA
- Mouse genes Fnta
- Rat genes Fnta
- Zfish genes fnta
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fnta

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030548	acetylcholine receptor regulator activity	Fnta	IMP		Mouse	PMID:14622576
Molecular Function	GO:0043014	alpha-tubulin binding	FNTA	IDA		Human	PMID:19228685
Molecular Function	GO:0004662	CAAX-protein geranylgeranyltransferase activity	Fnta	IDA		Rat	PMID:8089111\|RGD:2302973
Molecular Function	GO:1901363	heterocyclic compound binding	Fnta	IDA		Rat	PMID:15248757\|RGD:2302978
Molecular Function	GO:0008017	microtubule binding	FNTA	IDA		Human	PMID:19228685
Molecular Function	GO:0060090	molecular adaptor activity	FNTA	EXP		Human	PMID:11687658
Molecular Function	GO:0042277	peptide binding	Fnta	IDA		Rat	PMID:9705207\|RGD:2302975
Molecular Function	GO:0005515	protein binding	FNTA	IPI	UniProtKB:P49356	Human	PMID:11687658
Molecular Function	GO:0005515	protein binding	FNTA	IPI	UniProtKB:P49356	Human	PMID:12036349
Molecular Function	GO:0005515	protein binding	FNTA	IPI	UniProtKB:P49356	Human	PMID:12825937
Molecular Function	GO:0005515	protein binding	FNTA	IPI	UniProtKB:P49356	Human	PMID:15170324
Molecular Function	GO:0005515	protein binding	FNTA	IPI	UniProtKB:P49356	Human	PMID:15248757
Molecular Function	GO:0005515	protein binding	FNTA	IPI	UniProtKB:P49356	Human	PMID:15451670
Molecular Function	GO:0005515	protein binding	FNTA	IPI	UniProtKB:P49356	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	FNTA	IPI	UniProtKB:P53609	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	FNTA	IPI	UniProtKB:O00189	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FNTA	IPI	UniProtKB:P49356	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FNTA	IPI	UniProtKB:P53609	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Fnta	IPI	UniProtKB:Q02293	Rat	PMID:10377218\|RGD:8553653
Molecular Function	GO:0005515	protein binding	Fnta	IPI	UniProtKB:P01116-2	Rat	PMID:10673434\|RGD:11041072
Molecular Function	GO:0005515	protein binding	Fnta	IPI	UniProtKB:Q02293	Rat	PMID:10673434\|RGD:11041072
Molecular Function	GO:0005515	protein binding	Fnta	IPI	UniProtKB:Q02293	Rat	PMID:12657282\|RGD:8554767
Molecular Function	GO:0005515	protein binding	Fnta	IPI	UniProtKB:Q02293	Rat	PMID:12657283\|RGD:8554769
Molecular Function	GO:0005515	protein binding	Fnta	IPI	UniProtKB:Q02293	Rat	PMID:12657284\|RGD:8554772
Molecular Function	GO:0005515	protein binding	Fnta	IPI	UniProtKB:Q02293	Rat	PMID:12667062\|RGD:8554159
Molecular Function	GO:0005515	protein binding	Fnta	IPI	UniProtKB:Q02293	Rat	PMID:12699757\|RGD:8554635
Molecular Function	GO:0005515	protein binding	Fnta	IPI	UniProtKB:P53610	Rat	PMID:14609943\|RGD:8554040
Molecular Function	GO:0005515	protein binding	Fnta	IPI	UniProtKB:Q02293	Rat	PMID:15170324\|RGD:8553865
Molecular Function	GO:0005515	protein binding	Fnta	IPI	RGD:621754	Rat	PMID:15248757\|RGD:2302978
Molecular Function	GO:0005515	protein binding	Fnta	IPI	UniProtKB:P53610	Rat	PMID:15248757\|RGD:2302978
Molecular Function	GO:0005515	protein binding	Fnta	IPI	UniProtKB:P01116-2	Rat	PMID:15451670\|RGD:8553417
Molecular Function	GO:0005515	protein binding	Fnta	IPI	UniProtKB:P53610	Rat	PMID:15451670\|RGD:8553417
Molecular Function	GO:0005515	protein binding	Fnta	IPI	UniProtKB:Q02293	Rat	PMID:15451670\|RGD:8553417
Molecular Function	GO:0005515	protein binding	Fnta	IPI	RGD:3213	Rat	PMID:18957540\|RGD:2302981
Molecular Function	GO:0005515	protein binding	Fnta	IPI	UniProtKB:P53610	Rat	PMID:18957540\|RGD:2302981
Molecular Function	GO:0005515	protein binding	Fnta	IPI	UniProtKB:Q63604	Rat	PMID:18957540\|RGD:2302981
Molecular Function	GO:0005515	protein binding	Fnta	IPI	UniProtKB:Q02293	Rat	PMID:9065406\|RGD:13432295
Molecular Function	GO:0004660	protein farnesyltransferase activity	FNTA	IDA		Human	PMID:19228685
Molecular Function	GO:0004660	protein farnesyltransferase activity	FNTA	IDA		Human	PMID:16893176
Molecular Function	GO:0004660	protein farnesyltransferase activity	Fnta	IDA		Mouse	MGI:MGI:2680892\|PMID:14622576
Molecular Function	GO:0004660	protein farnesyltransferase activity	Fnta	IDA		Rat	PMID:8089111\|RGD:2302973
Molecular Function	GO:0004660	protein farnesyltransferase activity	Fnta	IDA		Rat	PMID:1763049\|RGD:728420
Molecular Function	GO:0004661	protein geranylgeranyltransferase activity	FNTA	IDA		Human	PMID:16893176
Molecular Function	GO:0004663	Rab geranylgeranyltransferase activity	Fnta	IDA		Mouse	MGI:MGI:2680892\|PMID:14622576
Molecular Function	GO:0030971	receptor tyrosine kinase binding	Fnta	IPI	UniProtKB:Q61006	Mouse	MGI:MGI:2680892\|PMID:14622576
Molecular Function	GO:0036094	small molecule binding	Fnta	IDA		Rat	PMID:15248757\|RGD:2302978
Molecular Function	GO:0008270	zinc ion binding	Fnta	IDA		Rat	PMID:15248757\|RGD:2302978
Cellular Component	GO:0005953	CAAX-protein geranylgeranyltransferase complex	FNTA	IDA		Human	PMID:16893176
Cellular Component	GO:0005953	CAAX-protein geranylgeranyltransferase complex	Fnta	IDA		Rat	PMID:15248757\|RGD:2302978
Cellular Component	GO:0005737	cytoplasm	Fnta	IDA		Rat	PMID:17192483\|RGD:2302980
Cellular Component	GO:0005875	microtubule associated complex	FNTA	IDA		Human	PMID:19228685
Cellular Component	GO:0005965	protein farnesyltransferase complex	FNTA	IDA		Human	PMID:16893176
Biological Process	GO:0043066	negative regulation of apoptotic process	Fnta	IMP		Rat	PMID:11313965\|RGD:2302977
Biological Process	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process	Fnta	IMP		Rat	PMID:9153192\|RGD:2302974
Biological Process	GO:0045213	neurotransmitter receptor metabolic process	Fnta	IMP		Mouse	PMID:14622576
Biological Process	GO:0045787	positive regulation of cell cycle	Fnta	IMP		Rat	PMID:10544242\|RGD:2302976
Biological Process	GO:0008284	positive regulation of cell population proliferation	Fnta	IMP		Rat	PMID:10544242\|RGD:2302976
Biological Process	GO:0090045	positive regulation of deacetylase activity	FNTA	IDA		Human	PMID:19228685
Biological Process	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process	Fnta	IMP		Rat	PMID:9153192\|RGD:2302974
Biological Process	GO:0090044	positive regulation of tubulin deacetylation	FNTA	IDA		Human	PMID:19228685
Biological Process	GO:0018343	protein farnesylation	FNTA	IDA		Human	PMID:16893176
Biological Process	GO:0018343	protein farnesylation	FNTA	IDA		Human	PMID:19228685
Biological Process	GO:0018344	protein geranylgeranylation	FNTA	IDA		Human	PMID:16893176
Biological Process	GO:0034097	response to cytokine	Fnta	IMP		Rat	PMID:9153192\|RGD:2302974
Biological Process	GO:0010035	response to inorganic substance	Fnta	IMP		Rat	PMID:18957540\|RGD:2302981
Biological Process	GO:0014070	response to organic cyclic compound	Fnta	IMP		Rat	PMID:16257390\|RGD:2302979

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/25/2025 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.