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Fnta Gene Detail
Summary
  • Symbol
    Fnta
  • Name
    farnesyltransferase, CAAX box, alpha
  • Synonyms
    FTA
  • Feature Type
    protein coding gene
  • IDs
    MGI:104683
    NCBI Gene: 14272
  • Gene Overview
    MyGene.info: FNTA
Location & Maps
more
  • Sequence Map
    Chr8:25998729-26015601 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      16873 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 14.27 cM
  • Detailed Genetic Map ± 1 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    FNTA, farnesyltransferase, CAAX box, alpha
  • Vertebrate Orthologs
    9
  • Human Ortholog
    FNTA, farnesyltransferase, CAAX box, alpha
    Orthology source: HGNC, HomoloGene
  • Synonyms
    FPTA, PGGT1A, PTAR2
  • Links
    NCBI Gene ID: 2339
    neXtProt AC: NX_P49354

  • Chr Location
    8p11; chr8:43056299-43085788 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 1534
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: FNTA
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    6
  • Gene trapped
    3
  • Targeted
    3
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000015994 Ensembl Gene Model | MGI Sequence Detail 16873 C57BL/6J ±  kb
transcript ENSMUST00000016138 Ensembl | MGI Sequence Detail 1874 Not Applicable  
polypeptide ENSMUSP00000016138 Ensembl | MGI Sequence Detail 377 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    179 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000007591 protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
  • PDB
  • EC
  • InterPro Domains
    IPR002088 Protein prenyltransferase, alpha subunit
Molecular
Reagents
less
  • All nucleic 164
    cDNA 162
    Primer pair 2

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-27046
References
more
  • Summaries
    All 34
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 7
  • Earliest
    J:29641 Shirasawa H, et al., Cloning and sequencing of the murine farnesyltransferase alpha-encoding cDNA from a cell line which expresses the human papillomavirus type-16 E6 gene. Gene. 1995 Oct 27;164(2):373-4
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/24/2016
MGI 6.04
The Jackson Laboratory