Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FLRT2
  • Mouse genes Flrt2
  • Rat genes Flrt2
  • Zfish genes flrt2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Flrt2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045499	chemorepellent activity	Flrt2	IDA		Mouse	PMID:21673655
Molecular Function	GO:0005104	fibroblast growth factor receptor binding	Flrt2	IPI	UniProtKB:P16092	Mouse	MGI:MGI:3662950|PMID:16872596
Molecular Function	GO:0005515	protein binding	Flrt2	IPI	UniProtKB:Q80TS3	Mouse	MGI:MGI:5688816|PMID:25728924
Molecular Function	GO:0005515	protein binding	Flrt2	IPI	PR:Q8K1S2	Mouse	PMID:21673655
Cellular Component	GO:0005911	cell-cell junction	Flrt2	IDA		Mouse	MGI:MGI:3662950|PMID:16872596
Cellular Component	GO:0070062	extracellular exosome	FLRT2	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	Flrt2	IDA		Mouse	PMID:21673655
Cellular Component	GO:0005925	focal adhesion	FLRT2	HDA		Human	PMID:21423176
Cellular Component	GO:0005925	focal adhesion	Flrt2	IDA		Mouse	MGI:MGI:3662950|PMID:16872596
Cellular Component	GO:0005886	plasma membrane	Flrt2	IDA		Mouse	MGI:MGI:3662950|PMID:16872596
Biological Process	GO:0007411	axon guidance	Flrt2	IGI	MGI:MGI:2389364	Mouse	PMID:21673655
Biological Process	GO:0071711	basement membrane organization	Flrt2	IMP		Mouse	MGI:MGI:4950310|PMID:21350012
Biological Process	GO:0061343	cell adhesion involved in heart morphogenesis	Flrt2	IMP		Mouse	MGI:MGI:4950310|PMID:21350012
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	Flrt2	IMP		Mouse	MGI:MGI:3662950|PMID:16872596
Biological Process	GO:0003007	heart morphogenesis	Flrt2	IMP		Mouse	MGI:MGI:4950310|PMID:21350012
Biological Process	GO:0051965	positive regulation of synapse assembly	Flrt2	IDA		Mouse	PMID:24613359
Biological Process	GO:2001222	regulation of neuron migration	Flrt2	IGI	MGI:MGI:2389364	Mouse	PMID:21673655

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern