Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FIGLA
  • Mouse genes Figla
  • Rat genes Figla
  • Zfish genes figla
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Figla

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043425	bHLH transcription factor binding	FIGLA	IPI	UniProtKB:P15923-1	Human	PMID:15044608
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Figla	IDA		Mouse	MGI:MGI:1326792|PMID:9362457
Molecular Function	GO:0070888	E-box binding	FIGLA	IPI	UniProtKB:P15923-1	Human	PMID:15044608
Molecular Function	GO:0005515	protein binding	FIGLA	IPI	UniProtKB:P13349	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FIGLA	IPI	UniProtKB:P15172	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FIGLA	IPI	UniProtKB:P15173	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FIGLA	IPI	UniProtKB:P15884-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FIGLA	IPI	UniProtKB:Q68G74	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FIGLA	IPI	UniProtKB:Q7RTU1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FIGLA	IPI	UniProtKB:Q99081-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FIGLA	IPI	UniProtKB:Q9UBR4-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FIGLA	IPI	UniProtKB:Q9UPM6	Human	PMID:32296183
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Figla	IDA		Mouse	MGI:MGI:1326792|PMID:9362457
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	FIGLA	IDA		Human	PMID:28473536
Cellular Component	GO:0005667	transcription regulator complex	FIGLA	IDA		Human	PMID:15044608
Biological Process	GO:0008585	female gonad development	figla	IEP		Zfish	PMID:14579378
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Figla	IDA		Mouse	MGI:MGI:1326792|PMID:9362457

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern