Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FGF12
  • Mouse genes Fgf12
  • Rat genes Fgf12
  • Zfish genes fgf12a,fgf12b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fgf12

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	FGF12	IPI	UniProtKB:P32321	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FGF12	IPI	UniProtKB:P38432	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FGF12	IPI	UniProtKB:Q13422	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FGF12	IPI	UniProtKB:Q14592	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FGF12	IPI	UniProtKB:Q9BRK4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FGF12	IPI	UniProtKB:Q9UI36-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	Fgf12	IPI	PR:Q9R053	Mouse	PMID:11376006
Molecular Function	GO:0005515	protein binding	Fgf12	IPI	RGD:3630	Rat	PMID:11376006|RGD:632803
Molecular Function	GO:0005515	protein binding	Fgf12	IPI	RGD:3637	Rat	PMID:12401812|RGD:6484231
Molecular Function	GO:0017080	sodium channel regulator activity	Fgf12	IDA		Rat	PMID:12401812|RGD:6484231
Molecular Function	GO:0044325	transmembrane transporter binding	Fgf12	IPI	UniProtKB:O88457	Rat	PMID:12401812|RGD:6484231
Molecular Function	GO:0044325	transmembrane transporter binding	Fgf12	IPI	UniProtKB:Q14524	Rat	PMID:12401812|RGD:6484231
Cellular Component	GO:0005634	nucleus	FGF12	IDA		Human	PMID:8790420
Biological Process	GO:0008344	adult locomotory behavior	Fgf12	IGI	MGI:MGI:109189	Mouse	PMID:17678857
Biological Process	GO:0007268	chemical synaptic transmission	Fgf12	IGI	MGI:MGI:109189	Mouse	PMID:17678857
Biological Process	GO:2001258	negative regulation of cation channel activity	Fgf12	IDA		Rat	PMID:12401812|RGD:6484231
Biological Process	GO:0050905	neuromuscular process	Fgf12	IGI	MGI:MGI:109189	Mouse	PMID:17678857
Biological Process	GO:0010765	positive regulation of sodium ion transport	Fgf12	IGI	MGI:MGI:109189	Mouse	PMID:17678857
Biological Process	GO:0003254	regulation of membrane depolarization	Fgf12	IDA		Rat	PMID:12401812|RGD:6484231
Biological Process	GO:0098908	regulation of neuronal action potential	FGF12	IMP		Human	PMID:27164707
Biological Process	GO:1902305	regulation of sodium ion transmembrane transport	Fgf12	IDA		Rat	PMID:12401812|RGD:6484231
Biological Process	GO:2000649	regulation of sodium ion transmembrane transporter activity	Fgf12	IDA		Rat	PMID:12401812|RGD:6484231
Biological Process	GO:1905150	regulation of voltage-gated sodium channel activity	FGF12	IMP		Human	PMID:27164707

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern