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Fgf12
Gene Detail
 Symbol
Name
ID
Fgf12
fibroblast growth factor 12
MGI:109183
Synonyms Fhf1
Feature Type protein coding gene
Genetic Map
Chromosome 16
19.38 cM, cytoband B1-B3
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr16:28160120-28445227 bp, - strand
From Ensembl annotation of GRCm38

  285108 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10874  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Fgf12

Human
homologs
Human Homolog FGF12, fibroblast growth factor 12
NCBI Gene ID 2257
neXtProt AC  NX_P61328
Human Synonyms  FGF12B, FHF1
Human Chr (Location)  3q28; chr3:192139244-192727599 (-)  GRCh38
Alleles
and
phenotypes
All alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele are viable, fertile, and do not exhibit any significant behavioral or neurological phenotypes.
 
Gene Ontology
(GO)
classifications
All GO classifications: (19 annotations)
Process adult locomotory behavior, JNK cascade, ...
Component nucleus
Function growth factor activity, heparin binding, ...
External Resources: FuncBase
Expression
Literature Summary: (20 records)
Data Summary: Results (236)    Tissues (203)    Images (47)
Theiler Stages: 15, 17, 19, 20, 21, 22, 23, 24, 25, 26, 28
Assay TypeResults
RNA in situ 221
RT-PCR 15
cDNA source data(27)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(36) Genomic(1) cDNA(29) Primer pair(5) Other(1)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000022523 (Evidence)
Entrez Gene14167 (Evidence)
UniGene7996
DFCITC1581938, TC1604230, TC1645639, TC1651407
DoTSDT.40139510, DT.60101891, DT.94122351, DT.97392394, DT.99854479
NIA Mouse Gene IndexU036940, U318918
Consensus CDS ProjectCCDS28092.1
International Mouse Knockout Project StatusFgf12
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022523 Ensembl Gene Model | MGI Sequence Detail 285108 C57BL/6J ±  kb
transcript ENSMUST00000100024 Ensembl | MGI Sequence Detail 3065 Not Applicable 
polypeptide ENSMUSP00000097601 Ensembl | MGI Sequence Detail 243 Not Applicable 

For the selected sequences
All sequences(47) RefSeq(10) UniProt(5)
Polymorphisms RFLP(1) : SNPs within 2kb(4654 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR008996 Cytokine, IL-1-like
InterPro IPR002209 Heparin-binding growth factor/Fibroblast growth factor
Protein Ontology PR:000007482 fibroblast growth factor 12
References (Earliest) J:41070 Smallwood PM, et al., Fibroblast growth factor (FGF) homologous factors: new members of the FGF family implicated in nervous system development. Proc Natl Acad Sci U S A. 1996 Sep 3;93(18):9850-7
(Latest) J:205051 Miller JA, et al., Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Development. 2013 Nov;140(22):4633-44
All references(52)
Other
accession IDs
MGD-MRK-38227, MGI:2146595

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory