About   Help   FAQ
Fgf12
Gene Detail
Symbol

Name
ID
Fgf12
fibroblast growth factor 12
MGI:109183
Synonyms
Fhf1
Feature Type
protein coding gene
Genetic Map
Chromosome 16
19.38 cM, cytoband B1-B3
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr16:28160120-28445227 bp, - strand
From Ensembl annotation of GRCm38

  285108 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10874  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: FGF12
Gene Tree: Fgf12

Human
homologs
FGF12, fibroblast growth factor 12
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 2257
neXtProt AC: NX_P61328

Human Synonyms: FGF12B, FHF1

Human Chr (Location): 3q28; chr3:192139244-192727599 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele are viable, fertile, and do not exhibit any significant behavioral or neurological phenotypes.
 
Interactions
Fgf12 interacts with 308 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (20 annotations)
Process adult locomotory behavior, JNK cascade, ...
Component intracellular, nucleus
Function growth factor activity, heparin binding, ...
External Resources: FuncBase
Expression
Literature Summary: (21 records)
Data Summary: Results (236)    Tissues (203)    Images (47)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 221
RT-PCR 15
cDNA source data(27)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: GEISHA FGF12 ; Xenbase fgf12    NEW 
Molecular
reagents
All nucleic(36) Genomic(1) cDNA(29) Primer pair(5) Other(1)
Microarray probesets(4)
Other database
links
Ensembl Gene Model ENSMUSG00000022523 (Evidence)
Entrez Gene 14167 (Evidence)
UniGene 7996
DFCI TC1645639, TC1604230, TC1581938, TC1651407
DoTS DT.60101891, DT.40139510, DT.94122351, DT.99854479, DT.97392394
NIA Mouse Gene Index U318918, U036940
Consensus CDS Project CCDS28092.1
International Mouse Phenotyping Consortium Status Fgf12
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022523 Ensembl Gene Model | MGI Sequence Detail 285108 C57BL/6J ±  kb
transcript ENSMUST00000100024 Ensembl | MGI Sequence Detail 3065 Not Applicable 
polypeptide ENSMUSP00000097601 Ensembl | MGI Sequence Detail 243 Not Applicable 

For the selected sequences
All sequences(48) RefSeq(10) UniProt(5)
Polymorphisms
RFLP(1) : SNPs within 2kb(4654 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR008996 Cytokine, IL-1-like
InterPro IPR002209 Heparin-binding growth factor/Fibroblast growth factor
Protein Ontology PR:000007482 fibroblast growth factor 12
References
(Earliest) J:41070 Smallwood PM, et al., Fibroblast growth factor (FGF) homologous factors: new members of the FGF family implicated in nervous system development. Proc Natl Acad Sci U S A. 1996 Sep 3;93(18):9850-7
(Latest) J:205051 Miller JA, et al., Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Development. 2013 Nov;140(22):4633-44
All references(54)
Other
accession IDs
MGD-MRK-38227, MGI:2146595

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/30/2015
MGI 5.22
The Jackson Laboratory