Fgf12
Gene Detail

Symbol Name ID

Fgf12 fibroblast growth factor 12 MGI:109183

Synonyms

Fhf1

Feature Type

protein coding gene

Genetic Map

Chromosome 16

19.38 cM, cytoband B1-B3
Detailed Genetic Map ± 1 cM


Mapping data(5)

Sequence Map

Chr16:28160120-28445227 bp, - strand From Ensembl annotation of GRCm38   285108 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:10874  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Fgf12

Human homologs

Human Homolog		FGF12, fibroblast growth factor 12
NCBI Gene ID		2257
neXtProt AC		NX_P61328
Human Synonyms		FGF12B, FHF1
Human Chr (Location)		3q28; chr3:191857182-192445388 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(2) : Targeted(2)
 

Mice homozygous for a knock-out allele are viable, fertile, and do not exhibit any significant behavioral or neurological phenotypes.

 

Gene Ontology (GO) classifications

All GO classifications: (13 annotations)

Process	adult locomotory behavior, JNK cascade, ...
Component	nucleus
Function	growth factor activity, heparin binding, ...

External Resources: FuncBase

Expression

Literature Summary: (19 records)
Data Summary: Results (187)    Tissues (154)    Images (45)
Theiler Stages: 15, 17, 19, 20, 21, 22, 23, 24, 25, 28

Assay Type	Results
RNA in situ	172
RT-PCR	15

cDNA source data(27)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(36) Genomic(1) cDNA(29) Primer pair(5) Other(1)
Microarray probesets(4)

Other database links

Ensembl Gene Model	ENSMUSG00000022523 (Evidence)
Entrez Gene	14167 (Evidence)
UniGene	7996
DFCI	TC1581938, TC1604230, TC1645639, TC1651407
DoTS	DT.40139510, DT.60101891, DT.94122351, DT.97392394, DT.99854479
NIA Mouse Gene Index	U036940, U318918
Consensus CDS Project	CCDS28092.1
International Mouse Knockout Project Status	Fgf12

Sequences

Length	Strain/Species
genomic	ENSMUSG00000022523	Ensembl Gene Model | MGI Sequence Detail	285108	C57BL/6J
transcript	ENSMUST00000100024	Ensembl | MGI Sequence Detail	3065	Not Applicable
polypeptide	ENSMUSP00000097601	Ensembl | MGI Sequence Detail	243	Not Applicable

All sequences(45) RefSeq(8) UniProt(5)

Polymorphisms

RFLP(1) : SNPs(3019 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR008996	Cytokine, IL-1-like
InterPro	IPR002209	Heparin-binding growth factor/Fibroblast growth factor
InterPro	IPR002348	Interleukin 1/heparin-binding growth factor
Protein Ontology	PR:000007482	fibroblast growth factor 12

References

(Earliest) J:41070 Smallwood PM, et al., Fibroblast growth factor (FGF) homologous factors: new members of the FGF family implicated in nervous system development. Proc Natl Acad Sci U S A. 1996 Sep 3;93(18):9850-7
(Latest) J:194049 Johansson PA, et al., The transcription factor Otx2 regulates choroid plexus development and function. Development. 2013 Mar;140(5):1055-66
All references(51)

Other accession IDs

MGD-MRK-38227, MGI:2146595