Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FCHO1
  • Mouse genes Fcho1
  • Rat genes Fcho1
  • Zfish genes fcho1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fcho1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035612	AP-2 adaptor complex binding	FCHO1	IDA		Human	PMID:22484487
Molecular Function	GO:0005515	protein binding	FCHO1	IPI	UniProtKB:A7BFV9	Human	PMID:19713939
Molecular Function	GO:0005515	protein binding	FCHO1	IPI	UniProtKB:Q13882	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FCHO1	IPI	UniProtKB:Q8TCE9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FCHO1	IPI	UniProtKB:Q9NQT4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FCHO1	IPI	UniProtKB:Q13882	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	FCHO1	IPI	UniProtKB:Q8TCE9	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	FCHO1	IPI	UniProtKB:Q9NQT4	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	Fcho1	IPI	UniProtKB:Q9CR95	Mouse	MGI:MGI:5917753|PMID:24130457
Cellular Component	GO:0005905	clathrin-coated pit	FCHO1	IDA		Human	PMID:20448150
Cellular Component	GO:0005905	clathrin-coated pit	FCHO1	IDA		Human	PMID:22484487
Cellular Component	GO:0005829	cytosol	FCHO1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	FCHO1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	FCHO1	IDA		Human	PMID:20448150
Cellular Component	GO:0005886	plasma membrane	fcho1	IDA		Zfish	PMID:22484487
Biological Process	GO:0030509	BMP signaling pathway	fcho1	IGI	ZFIN:ZDB-MRPHLNO-060920-2,ZFIN:ZDB-MRPHLNO-120614-7	Zfish	PMID:22484487
Biological Process	GO:0048268	clathrin coat assembly	FCHO1	IMP		Human	PMID:20448150
Biological Process	GO:0048268	clathrin coat assembly	FCHO1	IMP		Human	PMID:32098969
Biological Process	GO:0072583	clathrin-dependent endocytosis	FCHO1	IMP		Human	PMID:20448150
Biological Process	GO:0072583	clathrin-dependent endocytosis	FCHO1	IMP		Human	PMID:32098969
Biological Process	GO:0009953	dorsal/ventral pattern formation	fcho1	IMP	ZFIN:ZDB-MRPHLNO-120614-7	Zfish	PMID:22484487
Biological Process	GO:0009953	dorsal/ventral pattern formation	fcho1	IGI	ZFIN:ZDB-MRPHLNO-060920-2,ZFIN:ZDB-MRPHLNO-120614-7	Zfish	PMID:22484487
Biological Process	GO:0050870	positive regulation of T cell activation	FCHO1	IMP		Human	PMID:32098969
Biological Process	GO:0050852	T cell receptor signaling pathway	FCHO1	IMP		Human	PMID:32098969

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern