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Fcho1 Gene Detail
Summary
  • Symbol
    Fcho1
  • Name
    FCH domain only 1
  • Synonyms
    3322402E17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921265
    NCBI Gene: 74015
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:71708387-71725703 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 34.43 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    80 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921265
 protein coding gene Chr8:71708387-71725716 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033763
 protein coding gene Chr8:72124567-72141780 (-)
A/J MGP_AJ_G0033746
 protein coding gene Chr8:69186253-69203582 (-)
AKR/J MGP_AKRJ_G0033672
 protein coding gene Chr8:71238197-71255422 (-)
BALB/cJ MGP_BALBcJ_G0033742
 protein coding gene Chr8:69370573-69387786 (-)
C3H/HeJ MGP_C3HHeJ_G0033452
 protein coding gene Chr8:71806914-71824127 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034260
 protein coding gene Chr8:74869223-74886552 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031202
 protein coding gene Chr8:63818113-63835439 (-)
CAST/EiJ MGP_CASTEiJ_G0032777
 protein coding gene Chr8:71266214-71283494 (-)
CBA/J MGP_CBAJ_G0033430
 protein coding gene Chr8:77519935-77537148 (-)
DBA/2J MGP_DBA2J_G0033584
 protein coding gene Chr8:68910500-68927713 (-)
FVB/NJ MGP_FVBNJ_G0033526
 protein coding gene Chr8:68011259-68028472 (-)
LP/J MGP_LPJ_G0033671
 protein coding gene Chr8:72110108-72127321 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033573
 protein coding gene Chr8:80055150-80072479 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034277
 protein coding gene Chr8:71289631-71306844 (-)
PWK/PhJ MGP_PWKPhJ_G0032484
 protein coding gene Chr8:68200746-68218077 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032321
 protein coding gene Chr8:70245429-70262639 (-)
WSB/EiJ MGP_WSBEiJ_G0032893
 protein coding gene Chr8:71640881-71658113 (-)



Homology
more
  • Human Ortholog
    FCHO1, FCH and mu domain containing endocytic adaptor 1
  • Vertebrate Orthologs
    8
  • Human Ortholog
    FCHO1, FCH and mu domain containing endocytic adaptor 1
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 23149
    neXtProt AC: NX_O14526
    UniProt: O14526

  • Chr Location
    19p13.11; chr19:17747718-17788568 (+)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    69
  • Tissues
    8
  • cDNA Data
    51
  • Literature Summary
    1
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 74015 NCBI Gene Model | MGI Sequence Detail 17317 C57BL/6J ±  kb
transcript NR_028267 RefSeq | MGI Sequence Detail 3399 C57BL/6  
polypeptide Q8K285 UniProt | EBI | MGI Sequence Detail 873 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 51
    cDNA 51

    Microarray probesets 4
Other
Accession IDs
less
MGI:2142889
References
more
  • Summaries
    All 30
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:245326 Ritter B, et al., NECAP 1 regulates AP-2 interactions to control vesicle size, number, and cargo during clathrin-mediated endocytosis. PLoS Biol. 2013 Oct;11(10):e1001670
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/15/2019
MGI 6.14 		The Jackson Laboratory