Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FBXO3
  • Mouse genes Fbxo3
  • Rat genes Fbxo3
  • Zfish genes fbxo3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fbxo3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	FBXO3	IPI	UniProtKB:Q13616	Human	PMID:21145461
Molecular Function	GO:0005515	protein binding	FBXO3	IPI	UniProtKB:P63208	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	FBXO3	IPI	UniProtKB:P04608	Human	PMID:22190034
Molecular Function	GO:0005515	protein binding	FBXO3	IPI	UniProtKB:P63208	Human	PMID:22632967
Molecular Function	GO:0005515	protein binding	FBXO3	IPI	UniProtKB:P63208	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	FBXO3	IPI	UniProtKB:P63208	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	FBXO3	IPI	UniProtKB:P63208	Human	PMID:32296183
Molecular Function	GO:1990756	ubiquitin ligase-substrate adaptor activity	FBXO3	IDA		Human	PMID:26037928
Molecular Function	GO:1990756	ubiquitin ligase-substrate adaptor activity	Fbxo3	IDA		Mouse	MGI:MGI:5488521|PMID:23542741
Cellular Component	GO:0005829	cytosol	FBXO3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	FBXO3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0019005	SCF ubiquitin ligase complex	FBXO3	IDA		Human	PMID:26037928
Biological Process	GO:0032496	response to lipopolysaccharide	FBXO3	IDA		Human	PMID:26037928
Biological Process	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	FBXO3	IDA		Human	PMID:26037928
Biological Process	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	Fbxo3	IDA		Mouse	MGI:MGI:5488521|PMID:23542741

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern