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Fbxo3 Gene Detail
Summary
  • Symbol
    Fbxo3
  • Name
    F-box protein 3
  • Synonyms
    1200002G09Rik, 1700026K02Rik, Fba
  • Feature Type
    protein coding gene
  • IDs
    MGI:1929084
    NCBI Gene: 57443
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:104027799-104063237 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 54.49 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    187 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1929084
protein coding gene Chr2:104027721-104063240 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026210
protein coding gene Chr2:106049348-106087900 (+)
A/J MGP_AJ_G0026171
protein coding gene Chr2:101672800-101708154 (+)
AKR/J MGP_AKRJ_G0026152
protein coding gene Chr2:104405090-104440617 (+)
BALB/cJ MGP_BALBcJ_G0026180
protein coding gene Chr2:101948803-101983710 (+)
C3H/HeJ MGP_C3HHeJ_G0025931
protein coding gene Chr2:104751494-104785824 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026631
protein coding gene Chr2:109582426-109620951 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024022
protein coding gene Chr2:97324232-97359925 (+)
CAST/EiJ MGP_CASTEiJ_G0025396
protein coding gene Chr2:105227832-105266264 (+)
CBA/J MGP_CBAJ_G0025909
protein coding gene Chr2:113300729-113337090 (+)
DBA/2J MGP_DBA2J_G0026046
protein coding gene Chr2:101217629-101252384 (+)
FVB/NJ MGP_FVBNJ_G0026008
protein coding gene Chr2:100178726-100248194 (+)
LP/J MGP_LPJ_G0026149
protein coding gene Chr2:106163974-106203385 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026034
protein coding gene Chr2:117226206-117260920 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026685
protein coding gene Chr2:104635919-104675309 (+)
PWK/PhJ MGP_PWKPhJ_G0025131
protein coding gene Chr2:100730661-100765113 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024932
protein coding gene Chr2:103842119-103876638 (+)
WSB/EiJ MGP_WSBEiJ_G0025463
protein coding gene Chr2:105345398-105383946 (+)



Homology
more
  • Human Ortholog
    FBXO3, F-box protein 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    FBXO3, F-box protein 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    FBA, FBX3
  • Links
    NCBI Gene ID: 26273
    neXtProt AC: NX_Q9UK99
    UniProt: Q9UK99

  • Chr Location
    11p13; chr11:33740937-33774531 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 8133
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: FBXO3
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Gene trapped
    1
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Fbxo3
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 57443 NCBI Gene Model | MGI Sequence Detail 35439 C57BL/6J ±  kb
transcript NM_212433 RefSeq | MGI Sequence Detail 4659 Not Specified  
polypeptide Q9DC63 UniProt | EBI | MGI Sequence Detail 480 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 26
    cDNA 26

    Microarray probesets 11
Other
Accession IDs
less
MGI:1914700, MGI:1919505, MGI:2138830
References
more
  • Summaries
    All 33
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:229930 Nechiporuk T, et al., The REST remodeling complex protects genomic integrity during embryonic neurogenesis. Elife. 2016;5

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory