Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FBXL5
  • Mouse genes Fbxl5
  • Rat genes Fbxl5
  • Zfish genes fbxl5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fbxl5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005506	iron ion binding	FBXL5	IDA		Human	PMID:19762596
Molecular Function	GO:0005506	iron ion binding	FBXL5	IDA		Human	PMID:19762597
Molecular Function	GO:0005515	protein binding	FBXL5	IPI	UniProtKB:Q14203	Human	PMID:17532294
Molecular Function	GO:0005515	protein binding	FBXL5	IPI	UniProtKB:P21399	Human	PMID:19762596
Molecular Function	GO:0005515	protein binding	FBXL5	IPI	UniProtKB:P48200	Human	PMID:19762596
Molecular Function	GO:0005515	protein binding	FBXL5	IPI	UniProtKB:P21399	Human	PMID:19762597
Molecular Function	GO:0005515	protein binding	FBXL5	IPI	UniProtKB:P48200	Human	PMID:19762597
Molecular Function	GO:0005515	protein binding	FBXL5	IPI	UniProtKB:P63208	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	FBXL5	IPI	UniProtKB:P63208	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FBXL5	IPI	UniProtKB:P63208	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	FBXL5	IPI	UniProtKB:P63208	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FBXL5	IPI	UniProtKB:Q13148	Human	PMID:32814053
Cellular Component	GO:0048471	perinuclear region of cytoplasm	FBXL5	IDA		Human	PMID:17532294
Cellular Component	GO:0019005	SCF ubiquitin ligase complex	FBXL5	IDA		Human	PMID:19762596
Cellular Component	GO:0019005	SCF ubiquitin ligase complex	FBXL5	IDA		Human	PMID:19762597
Biological Process	GO:0006879	intracellular iron ion homeostasis	FBXL5	IMP		Human	PMID:19762596
Biological Process	GO:0006879	intracellular iron ion homeostasis	FBXL5	IEP		Human	PMID:19762597
Biological Process	GO:0060586	multicellular organismal-level iron ion homeostasis	Fbxl5	IGI	MGI:MGI:1928268	Mouse	PMID:21907140
Biological Process	GO:0060586	multicellular organismal-level iron ion homeostasis	Fbxl5	IMP	MGI:MGI:5295288	Mouse	PMID:21907140
Biological Process	GO:0045732	positive regulation of protein catabolic process	Fbxl5	IMP	MGI:MGI:5295289	Mouse	PMID:21907140
Biological Process	GO:0030163	protein catabolic process	Fbxl5	IMP	MGI:MGI:5295289	Mouse	PMID:21907140
Biological Process	GO:0016567	protein ubiquitination	FBXL5	IDA		Human	PMID:17532294
Biological Process	GO:0016567	protein ubiquitination	FBXL5	IDA		Human	PMID:19762596
Biological Process	GO:0016567	protein ubiquitination	FBXL5	IDA		Human	PMID:19762597
Biological Process	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	FBXL5	IDA		Human	PMID:17532294
Biological Process	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	FBXL5	IDA		Human	PMID:19762596
Biological Process	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	FBXL5	IDA		Human	PMID:19762597

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern