Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FAN1
  • Mouse genes Fan1
  • Rat genes Fan1
  • Zfish genes fan1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fan1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008409	5'-3' exonuclease activity	FAN1	IDA		Human	PMID:20603015
Molecular Function	GO:0008409	5'-3' exonuclease activity	FAN1	IDA		Human	PMID:20603016
Molecular Function	GO:0008409	5'-3' exonuclease activity	FAN1	IDA		Human	PMID:20603073
Molecular Function	GO:0008409	5'-3' exonuclease activity	FAN1	IDA		Human	PMID:24981866
Molecular Function	GO:0008409	5'-3' exonuclease activity	FAN1	IDA		Human	PMID:25430771
Molecular Function	GO:0008409	5'-3' exonuclease activity	Fan1	IDA		Mouse	MGI:MGI:5613747|PMID:24981866
Molecular Function	GO:0017108	5'-flap endonuclease activity	FAN1	IDA		Human	PMID:20603015
Molecular Function	GO:0017108	5'-flap endonuclease activity	FAN1	IDA		Human	PMID:20603016
Molecular Function	GO:0017108	5'-flap endonuclease activity	FAN1	IDA		Human	PMID:20603073
Molecular Function	GO:0017108	5'-flap endonuclease activity	FAN1	IDA		Human	PMID:24981866
Molecular Function	GO:0070336	flap-structured DNA binding	FAN1	IDA		Human	PMID:25430771
Molecular Function	GO:0005515	protein binding	FAN1	IPI	UniProtKB:Q9BXW9	Human	PMID:20603015
Molecular Function	GO:0005515	protein binding	FAN1	IPI	UniProtKB:Q9NVI1	Human	PMID:20603015
Molecular Function	GO:0005515	protein binding	FAN1	IPI	UniProtKB:Q9BXW9	Human	PMID:20603016
Molecular Function	GO:0005515	protein binding	FAN1	IPI	UniProtKB:P40692	Human	PMID:20603073
Molecular Function	GO:0005515	protein binding	FAN1	IPI	UniProtKB:P54278	Human	PMID:20603073
Molecular Function	GO:0005515	protein binding	FAN1	IPI	UniProtKB:Q9BXW9	Human	PMID:20603073
Molecular Function	GO:0005515	protein binding	FAN1	IPI	UniProtKB:Q9UHC1	Human	PMID:20603073
Molecular Function	GO:0140036	ubiquitin-dependent protein binding	FAN1	IDA		Human	PMID:20603015
Molecular Function	GO:0140036	ubiquitin-dependent protein binding	FAN1	IDA		Human	PMID:20603016
Cellular Component	GO:0005829	cytosol	FAN1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0045171	intercellular bridge	FAN1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	FAN1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	FAN1	IDA		Human	PMID:20603015
Cellular Component	GO:0005634	nucleus	FAN1	IDA		Human	PMID:20603016
Cellular Component	GO:0005634	nucleus	FAN1	IDA		Human	PMID:20603073
Biological Process	GO:0006281	DNA repair	FAN1	IMP		Human	PMID:20603073
Biological Process	GO:0000724	double-strand break repair via homologous recombination	FAN1	IMP		Human	PMID:20603015
Biological Process	GO:0000724	double-strand break repair via homologous recombination	FAN1	IMP		Human	PMID:20603016
Biological Process	GO:0036297	interstrand cross-link repair	FAN1	IDA		Human	PMID:25430771
Biological Process	GO:0006289	nucleotide-excision repair	FAN1	IDA		Human	PMID:20603015
Biological Process	GO:0006289	nucleotide-excision repair	FAN1	IMP		Human	PMID:20603016
Biological Process	GO:0006289	nucleotide-excision repair	FAN1	IDA		Human	PMID:25430771

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern