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Fan1
Gene Detail
Symbol

Name
ID
Fan1
FANCD2/FANCI-associated nuclease 1
MGI:3045266
Synonyms
6030441H18Rik, Mtmr15
Feature Type
protein coding gene
Genetic Map
Chromosome 7
34.64 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr7:64346758-64374095 bp, - strand
From VEGA annotation of GRCm38

  27338 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:45598  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Fan1

Human
homologs
Human Homolog FAN1, FANCD2/FANCI-associated nuclease 1
NCBI Gene ID 22909
neXtProt AC  NX_Q9Y2M0
Human Synonyms  KIAA1018, KMIN, MTMR15
Human Chr (Location)  15q13.2-q13.3; chr15:30832893-30943108 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human FAN1
Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Gene trapped(6) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
Expression
cDNA source data(3)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(3) cDNA(3)
Microarray probesets(1)
Other database
links
VEGA Gene ModelOTTMUSG00000026085 (Evidence)
Ensembl Gene ModelENSMUSG00000033458 (Evidence)
Entrez Gene330554 (Evidence)
UniGene236510
DFCITC1640647, TC1591459
DoTSDT.87056282, DT.103577822
NIA Mouse Gene IndexU028671
EC3.1.4.1, 3.1.21.-
Consensus CDS ProjectCCDS52265.1
International Mouse Knockout Project StatusFan1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026085 VEGA Gene Model | MGI Sequence Detail 27338 C57BL/6J ±  kb
transcript OTTMUST00000110531 VEGA | MGI Sequence Detail 3063 Not Applicable 
polypeptide OTTMUSP00000061671 VEGA | MGI Sequence Detail 1020 Not Applicable 

For the selected sequences
All sequences(29) RefSeq(6) UniProt(1)
Polymorphisms
SNPs within 2kb(392 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR014883 VRR-NUC domain
Protein Ontology PR:000032601 fanconi-associated nuclease 1
References
(Earliest) J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(28)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory