Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FAM83D
  • Mouse genes Fam83d
  • Rat genes Fam83d
  • Zfish genes fam83d
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fam83d

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019894	kinesin binding	FAM83D	IPI	UniProtKB:Q14807	Human	PMID:18485706
Molecular Function	GO:0008017	microtubule binding	FAM83D	IDA		Human	PMID:18485706
Molecular Function	GO:0005515	protein binding	FAM83D	IPI	UniProtKB:O75330	Human	PMID:22965910
Molecular Function	GO:0005515	protein binding	FAM83D	IPI	UniProtKB:P63167	Human	PMID:22965910
Molecular Function	GO:0005515	protein binding	FAM83D	IPI	UniProtKB:P48729	Human	PMID:23455922
Molecular Function	GO:0005515	protein binding	FAM83D	IPI	UniProtKB:Q969H0	Human	PMID:24344117
Molecular Function	GO:0005515	protein binding	FAM83D	IPI	UniProtKB:P48729	Human	PMID:29789297
Molecular Function	GO:0005515	protein binding	FAM83D	IPI	UniProtKB:P48729	Human	PMID:31338967
Molecular Function	GO:0019901	protein kinase binding	FAM83D	IPI	UniProtKB:P04049	Human	PMID:24736947
Cellular Component	GO:0005737	cytoplasm	FAM83D	IDA		Human	PMID:18445686
Cellular Component	GO:0005737	cytoplasm	FAM83D	IDA		Human	PMID:18485706
Cellular Component	GO:0005829	cytosol	FAM83D	IDA		Human	GO_REF:0000052
Cellular Component	GO:0045171	intercellular bridge	FAM83D	IDA		Human	GO_REF:0000052
Cellular Component	GO:0015630	microtubule cytoskeleton	FAM83D	IDA		Human	GO_REF:0000052
Cellular Component	GO:0072686	mitotic spindle	FAM83D	IDA		Human	GO_REF:0000052
Cellular Component	GO:0097431	mitotic spindle pole	FAM83D	IDA		Human	PMID:15561729
Cellular Component	GO:0097431	mitotic spindle pole	FAM83D	IDA		Human	PMID:18485706
Cellular Component	GO:0005819	spindle	FAM83D	IDA		Human	PMID:18445686
Biological Process	GO:0016477	cell migration	FAM83D	IDA		Human	PMID:24344117
Biological Process	GO:0008283	cell population proliferation	FAM83D	IDA		Human	PMID:24344117
Biological Process	GO:0008283	cell population proliferation	FAM83D	IDA		Human	PMID:25646692
Biological Process	GO:0001837	epithelial to mesenchymal transition	FAM83D	IDA		Human	PMID:24344117
Biological Process	GO:0051310	metaphase plate congression	FAM83D	IMP		Human	PMID:18485706
Biological Process	GO:1902808	positive regulation of cell cycle G1/S phase transition	FAM83D	IMP		Human	PMID:25646692
Biological Process	GO:1902480	protein localization to mitotic spindle	FAM83D	IMP		Human	PMID:18485706
Biological Process	GO:0070372	regulation of ERK1 and ERK2 cascade	FAM83D	IMP		Human	PMID:24736947
Biological Process	GO:0070372	regulation of ERK1 and ERK2 cascade	FAM83D	IMP		Human	PMID:25646692
Biological Process	GO:0042176	regulation of protein catabolic process	FAM83D	IDA		Human	PMID:24344117
Biological Process	GO:0032006	regulation of TOR signaling	FAM83D	IDA		Human	PMID:24344117

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern