Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FAM20A
  • Mouse genes Fam20a
  • Rat genes Fam20a
  • Zfish genes fam20a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fam20a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	FAM20A	IPI	UniProtKB:Q8IXL6	Human	PMID:25789606
Molecular Function	GO:0043539	protein serine/threonine kinase activator activity	FAM20A	IDA		Human	PMID:25789606
Cellular Component	GO:0005737	cytoplasm	Fam20a	IDA		Mouse	MGI:MGI:5574295|PMID:21549343
Cellular Component	GO:0005783	endoplasmic reticulum	Fam20a	IDA		Mouse	MGI:MGI:5644017|PMID:22900076
Cellular Component	GO:0070062	extracellular exosome	FAM20A	HDA		Human	PMID:19199708
Cellular Component	GO:0005615	extracellular space	FAM20A	IDA		Human	PMID:22582013
Cellular Component	GO:0005615	extracellular space	Fam20a	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Cellular Component	GO:0005794	Golgi apparatus	FAM20A	IDA		Human	PMID:22582013
Cellular Component	GO:0005794	Golgi apparatus	Fam20a	IDA		Mouse	MGI:MGI:5644017|PMID:22900076
Cellular Component	GO:0005794	Golgi apparatus	Fam20a	IDA		Mouse	MGI:MGI:5574286|PMID:23468644
Biological Process	GO:0031214	biomineral tissue development	FAM20A	IMP		Human	PMID:25789606
Biological Process	GO:0055074	calcium ion homeostasis	FAM20A	IMP		Human	PMID:23434854
Biological Process	GO:0070166	enamel mineralization	FAM20A	IMP		Human	PMID:21549343
Biological Process	GO:0070166	enamel mineralization	FAM20A	IMP		Human	PMID:21990045
Biological Process	GO:0070166	enamel mineralization	FAM20A	IMP		Human	PMID:23468644
Biological Process	GO:0070166	enamel mineralization	Fam20a	IMP	MGI:MGI:5432376	Mouse	PMID:22732358
Biological Process	GO:0001934	positive regulation of protein phosphorylation	FAM20A	IDA		Human	PMID:25789606
Biological Process	GO:0001934	positive regulation of protein phosphorylation	Fam20a	IDA		Mouse	MGI:MGI:5644081|PMID:25789606
Biological Process	GO:0009617	response to bacterium	Fam20a	IEP		Mouse	PMID:23012479
Biological Process	GO:0044691	tooth eruption	FAM20A	IMP		Human	PMID:21990045
Biological Process	GO:0044691	tooth eruption	FAM20A	IMP		Human	PMID:23434854
Biological Process	GO:0044691	tooth eruption	FAM20A	IMP		Human	PMID:23468644
Biological Process	GO:0044691	tooth eruption	FAM20A	IMP		Human	PMID:23697977

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern