About   Help   FAQ
Fam20a
Gene Detail
 Symbol
Name
ID
Fam20a
family with sequence similarity 20, member A
MGI:2388266
Feature Type protein coding gene
Genetic Map
Chromosome 11
72.37 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:109669749-109722279 bp, - strand
From VEGA annotation of GRCm38

  52531 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9719  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Fam20a

Human
homologs
Human Homolog FAM20A, family with sequence similarity 20, member A
NCBI Gene ID 54757
neXtProt AC  NX_Q96MK3
Human Synonyms  AIGFS, FP2747
Human Chr (Location)  17q24.2; chr17:68535116-68600954 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human FAM20A
Alleles
and
phenotypes
All alleles(3) : Targeted(3)
 
Mice homozygous for a knock-out allele exhibit abnormal ameloblast morphology, disrupted dental enamel formation in both incisor and molar teeth, abnormal kidney morphology, disseminated calcifications of muscular arteries, and intrapulmonary calcifications.
 
Gene Ontology
(GO)
classifications
All GO classifications: (4 annotations)
Process enamel mineralization
Component extracellular region, extracellular vesicular exosome
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(67)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(67) cDNA(67)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000003353 (Evidence)
Ensembl Gene ModelENSMUSG00000020614 (Evidence)
Entrez Gene208659 (Evidence)
UniGene208662
DFCITC1577195
DoTSDT.40144043, DT.87048303
NIA Mouse Gene IndexU033573
Consensus CDS ProjectCCDS25584.1
International Mouse Knockout Project StatusFam20a
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000003353 VEGA Gene Model | MGI Sequence Detail 52531 C57BL/6J ±  kb
transcript OTTMUST00000007030 VEGA | MGI Sequence Detail 3085 Not Applicable 
polypeptide OTTMUSP00000045543 VEGA | MGI Sequence Detail 541 Not Applicable 

For the selected sequences
All sequences(33) RefSeq(5) UniProt(1)
Polymorphisms SNPs within 2kb(137 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR009581 Domain of unknown function DUF1193
InterPro IPR024869 FAM20
Protein Ontology PR:000031680 protein FAM20A
References (Earliest) J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
(Latest) J:186384 Vogel P, et al., Amelogenesis Imperfecta and Other Biomineralization Defects in Fam20a and Fam20c Null Mice. Vet Pathol. 2012 Jun 25;
All references(33)
Other
accession IDs
MGI:2144241

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
04/15/2014
MGI 5.17
The Jackson Laboratory