Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FAF2
  • Mouse genes Faf2
  • Rat genes Faf2
  • Zfish genes faf2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Faf2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035473	lipase binding	FAF2	IDA		Human	PMID:23297223
Molecular Function	GO:0055102	lipase inhibitor activity	FAF2	IDA		Human	PMID:23297223
Molecular Function	GO:0005515	protein binding	FAF2	IPI	UniProtKB:P55072	Human	PMID:18711132
Molecular Function	GO:0005515	protein binding	FAF2	IPI	UniProtKB:P55072	Human	PMID:18775313
Molecular Function	GO:0005515	protein binding	FAF2	IPI	UniProtKB:Q5VVQ6	Human	PMID:19818707
Molecular Function	GO:0005515	protein binding	FAF2	IPI	UniProtKB:P55072	Human	PMID:22119785
Molecular Function	GO:0005515	protein binding	FAF2	IPI	UniProtKB:Q8NBM4	Human	PMID:22119785
Molecular Function	GO:0005515	protein binding	FAF2	IPI	UniProtKB:Q9UHD9	Human	PMID:24215460
Molecular Function	GO:0005515	protein binding	FAF2	IPI	UniProtKB:Q8NBM4	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	FAF2	IPI	UniProtKB:P55072	Human	PMID:29997244
Molecular Function	GO:0005515	protein binding	FAF2	IPI	UniProtKB:Q6UX01	Human	PMID:31073040
Molecular Function	GO:0005515	protein binding	Faf2	IPI	UniProtKB:Q8R1K1|UniProtKB:Q9D1E5	Mouse	MGI:MGI:6303730|PMID:31073040
Molecular Function	GO:0043130	ubiquitin binding	FAF2	IDA		Human	PMID:18775313
Molecular Function	GO:0031625	ubiquitin protein ligase binding	FAF2	IDA		Human	PMID:18775313
Cellular Component	GO:0005783	endoplasmic reticulum	FAF2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005783	endoplasmic reticulum	FAF2	IDA		Human	PMID:23297223
Cellular Component	GO:0005811	lipid droplet	FAF2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005811	lipid droplet	FAF2	IDA		Human	PMID:14741744
Cellular Component	GO:0005811	lipid droplet	FAF2	IDA		Human	PMID:23297223
Cellular Component	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex	FAF2	IDA		Human	PMID:18775313
Biological Process	GO:0034389	lipid droplet organization	FAF2	IMP		Human	PMID:23297223
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	Faf2	IMP		Mouse	MGI:MGI:5780912|PMID:26692333
Biological Process	GO:0030970	retrograde protein transport, ER to cytosol	FAF2	IMP		Human	PMID:25660456
Biological Process	GO:0030433	ubiquitin-dependent ERAD pathway	FAF2	IMP		Human	PMID:24215460

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern