Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FAAH
  • Mouse genes Faah
  • Rat genes Faah
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Faah

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0047372	acylglycerol lipase activity	Faah	IMP		Mouse	PMID:20657592
Molecular Function	GO:0047372	acylglycerol lipase activity	Faah	IDA		Rat	PMID:17649977|RGD:14397564
Molecular Function	GO:0004040	amidase activity	Faah	IDA		Rat	PMID:12734197|RGD:1625736
Molecular Function	GO:0017064	fatty acid amide hydrolase activity	FAAH	IDA		Human	PMID:9122178
Molecular Function	GO:0017064	fatty acid amide hydrolase activity	Faah	IDA		Rat	PMID:12734197|RGD:1625736
Molecular Function	GO:0017064	fatty acid amide hydrolase activity	Faah	IMP		Rat	PMID:17545313|RGD:1625723
Molecular Function	GO:0017064	fatty acid amide hydrolase activity	Faah	IDA		Rat	PMID:17649977|RGD:14397564
Molecular Function	GO:0017064	fatty acid amide hydrolase activity	Faah	IDA		Rat	PMID:9122178|RGD:8554689
Molecular Function	GO:0016788	hydrolase activity, acting on ester bonds	Faah	IDA		Rat	PMID:12734197|RGD:1625736
Molecular Function	GO:0042802	identical protein binding	Faah	IPI	RGD:61808	Rat	PMID:12459591|RGD:728491
Molecular Function	GO:0042802	identical protein binding	Faah	IMP		Rat	PMID:17158103|RGD:1625734
Molecular Function	GO:0042802	identical protein binding	Faah	IPI	UniProtKB:P97612	Rat	PMID:18753625|RGD:13432302
Molecular Function	GO:0008289	lipid binding	Faah	IDA		Rat	PMID:12734197|RGD:1625736
Molecular Function	GO:0005543	phospholipid binding	Faah	IMP		Rat	PMID:17158103|RGD:1625734
Molecular Function	GO:0005515	protein binding	FAAH	IPI	UniProtKB:Q7Z3S9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	Faah	IPI	UniProtKB:A0A0G2K916,UniProtKB:B2GV38,UniProtKB:B5DFN4,UniProtKB:D3Z941,UniProtKB:D4AA63,UniProtKB:F1M853,UniProtKB:P11250,UniProtKB:P51593,UniProtKB:P61107,UniProtKB:P62718,UniProtKB:Q09167,UniProtKB:Q498M4,UniProtKB:Q5PPJ6,UniProtKB:Q5PPK9,UniProtKB:Q63569,UniProtKB:Q6AYJ7	Rat	PMID:27191843|RGD:11344934
Cellular Component	GO:0031090	organelle membrane	Faah	IDA		Rat	PMID:9122178|RGD:8554689
Biological Process	GO:0009062	fatty acid catabolic process	FAAH	IDA		Human	PMID:9122178
Biological Process	GO:0009062	fatty acid catabolic process	Faah	IDA		Rat	PMID:12734197|RGD:1625736
Biological Process	GO:0009062	fatty acid catabolic process	Faah	IDA		Rat	PMID:17649977|RGD:14397564
Biological Process	GO:0009062	fatty acid catabolic process	Faah	IDA		Rat	PMID:9122178|RGD:8554689
Biological Process	GO:0006631	fatty acid metabolic process	Faah	IMP		Rat	PMID:17545313|RGD:1625723
Biological Process	GO:0052651	monoacylglycerol catabolic process	Faah	IDA		Rat	PMID:17649977|RGD:14397564
Biological Process	GO:0045907	positive regulation of vasoconstriction	Faah	IMP		Rat	PMID:17245358|RGD:1625725

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern