Faah
Gene Detail

Symbol

Name
ID

BioType Conflict

Faah
fatty acid amide hydrolase
MGI:109609

Feature Type

protein coding gene

Genetic Map

Chromosome 4
53.08 cM
Detailed Genetic Map ± 1 cM


Mapping data(5)

Sequence Map

Chr4:115967145-116017926 bp, - strand From VEGA annotation of GRCm38   50782 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate
homology

Protein SuperFamily: amidase, fungal type
Gene Tree: Faah

Mutations,
alleles, and
phenotypes

All mutations/alleles(3) : Targeted(3)
Genomic Mutations involving Faah (1)
Incidental mutations (data from Mutagenetix , APF )
 

Mice homozygous for disruptions in this gene show a normal phenotype.

 

Interactions

Faah interacts with 220 markers (Mir9-1, Mir9-2, Mir9-3, ...)

View All

Gene Ontology
(GO)
classifications

All GO classifications: (7 annotations)

Component	endoplasmic reticulum, Golgi apparatus, ...
Function	acylglycerol lipase activity, carbon-nitrogen ligase activity, with glutamine as amido-N-donor, ...

External Resources: FuncBase

Expression

Literature Summary: (5 records)

Data Summary: Results (165)    Tissues (24)    Images (39)    Tissue x Stage Matrix (view)

Assay Type	Results
RNA in situ	165

cDNA source data(71)
External Resources: Allen Institute   Expression Atlas

Molecular
reagents

All nucleic(74) Genomic(1) cDNA(71) Primer pair(2)
Microarray probesets(5)

Other database
links

VEGA Gene Model	OTTMUSG00000008726 (Evidence)
Ensembl Gene Model	ENSMUSG00000034171 (Evidence)
Entrez Gene	14073, 102637048
UniGene	256025
DFCI	TC1590719, TC1574604, TC1608076, TC1740699
DoTS	DT.101159327, DT.101123164, DT.91316230, DT.55207737, DT.50315535
EC	3.5.1.99
Consensus CDS Project	CCDS18501.1
International Mouse Knockout Project Status	Faah

Sequences

Length	Strain/Species
genomic	OTTMUSG00000008726	VEGA Gene Model | MGI Sequence Detail	50782	C57BL/6J
transcript	OTTMUST00000019833	VEGA | MGI Sequence Detail	3827	Not Applicable
polypeptide	OTTMUSP00000009093	VEGA | MGI Sequence Detail	579	Not Applicable

All sequences(57) UniProt(4)

Polymorphisms

PCR(1) : SNPs within 2kb(180 from dbSNP Build 137)

Protein-related
information

Resource	ID	Description
InterPro	IPR000120	Amidase
InterPro	IPR020556	Amidase, conserved site
InterPro	IPR015830	Amidase, fungi
InterPro	IPR023631	Amidase signature domain
Protein Ontology	PR:000007305	fatty-acid amide hydrolase 1

References

(Earliest) J:39332 Giang DK, et al., Molecular characterization of human and mouse fatty acid amide hydrolases. Proc Natl Acad Sci U S A. 1997 Mar 18;94(6):2238-42
(Latest) J:208387 Dainese E, et al., Membrane lipids are key modulators of the endocannabinoid-hydrolase FAAH. Biochem J. 2014 Feb 1;457(3):463-72
All references(88)

Other
accession IDs

MGD-MRK-39608, MGI:2140571