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Faah
Gene Detail
Symbol

Name
ID
Faah
fatty acid amide hydrolase
MGI:109609
Feature Type
protein coding gene
Genetic Map
Chromosome 4
53.08 cM
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr4:115967145-116017926 bp, - strand
From VEGA annotation of GRCm38

  50782 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:68184  Vertebrate Homology Class
1 human; 1 mouse; 2 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Protein SuperFamily: amidase, fungal type
Gene Tree: Faah

Human
homologs
Human Homolog FAAH, fatty acid amide hydrolase
NCBI Gene ID 2166
neXtProt AC  NX_O00519
Human Synonyms  FAAH-1, PSAB
Human Chr (Location)  1p35-p34; chr1:46394267-46413848 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human FAAH
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for disruptions in this gene show a normal phenotype.
 
Interactions
Faah interacts with 220 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (17 annotations)
Process fatty acid catabolic process
Component endoplasmic reticulum, Golgi apparatus, ...
Function acylglycerol lipase activity, amidase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (165)    Tissues (24)    Images (39)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 165
cDNA source data(71)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(74) Genomic(1) cDNA(71) Primer pair(2)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000008726 (Evidence)
Ensembl Gene ModelENSMUSG00000034171 (Evidence)
Entrez Gene14073 (Evidence)
UniGene256025
DFCITC1574604, TC1590719, TC1608076, TC1740699
DoTSDT.101123164, DT.101123172, DT.101159327, DT.50315535, DT.55207737, DT.91316230
EC3.5.1.99
Consensus CDS ProjectCCDS18501.1
International Mouse Knockout Project StatusFaah
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000008726 VEGA Gene Model | MGI Sequence Detail 50782 C57BL/6J ±  kb
transcript OTTMUST00000019833 VEGA | MGI Sequence Detail 3827 Not Applicable 
polypeptide OTTMUSP00000009093 VEGA | MGI Sequence Detail 579 Not Applicable 

For the selected sequences
All sequences(70) RefSeq(6) UniProt(7)
Polymorphisms
PCR(1) : SNPs within 2kb(180 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000120 Amidase
InterPro IPR020556 Amidase, conserved site
InterPro IPR015830 Amidase, fungi
InterPro IPR023631 Amidase signature domain
Protein Ontology PR:000007305 fatty-acid amide hydrolase 1
References
(Earliest) J:39332 Giang DK, et al., Molecular characterization of human and mouse fatty acid amide hydrolases. Proc Natl Acad Sci U S A. 1997 Mar 18;94(6):2238-42
(Latest) J:208387 Dainese E, et al., Membrane lipids are key modulators of the endocannabinoid-hydrolase FAAH. Biochem J. 2014 Feb 1;457(3):463-72
All references(89)
Other
accession IDs
MGD-MRK-39608, MGI:2140571

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/21/2014
MGI 5.20
The Jackson Laboratory