Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ESCO2
  • Mouse genes Esco2
  • Rat genes Esco2
  • Zfish genes esco2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Esco2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016407	acetyltransferase activity	ESCO2	IDA		Human	PMID:15958495
Molecular Function	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor	Esco2	IMP	MGI:MGI:5308063	Mouse	PMID:22101327
Molecular Function	GO:0005515	protein binding	ESCO2	IPI	UniProtKB:P51114-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ESCO2	IPI	UniProtKB:Q08379	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ESCO2	IPI	UniProtKB:Q15276	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ESCO2	IPI	UniProtKB:Q9NRD5	Human	PMID:32296183
Cellular Component	GO:0030054	cell junction	ESCO2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0000785	chromatin	ESCO2	IDA		Human	PMID:19907496
Cellular Component	GO:0010369	chromocenter	Esco2	IDA		Mouse	PMID:22101327
Cellular Component	GO:0005694	chromosome	ESCO2	IDA		Human	PMID:15958495
Cellular Component	GO:0005794	Golgi apparatus	ESCO2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	ESCO2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005721	pericentric heterochromatin	Esco2	IDA		Mouse	PMID:22101327
Cellular Component	GO:0035861	site of double-strand break	Esco2	IDA		Mouse	PMID:22614755
Cellular Component	GO:0035861	site of double-strand break	Esco2	IDA		Mouse	PMID:22699483
Cellular Component	GO:0001741	XY body	Esco2	IDA		Mouse	PMID:22699483
Biological Process	GO:1990523	bone regeneration	esco2	IMP	ZFIN:ZDB-MRPHLNO-110713-1	Zfish	PMID:26434741
Biological Process	GO:0007059	chromosome segregation	Esco2	IMP	MGI:MGI:5308063	Mouse	PMID:22101327
Biological Process	GO:0006302	double-strand break repair	Esco2	IMP	MGI:MGI:5308063	Mouse	PMID:22614755
Biological Process	GO:0031101	fin regeneration	esco2	IMP	ZFIN:ZDB-MRPHLNO-110713-1	Zfish	PMID:26434741
Biological Process	GO:0031101	fin regeneration	esco2	IGI	ZFIN:ZDB-GENO-120514-7,ZFIN:ZDB-MRPHLNO-110713-1	Zfish	PMID:26434741
Biological Process	GO:0007507	heart development	esco2	IMP	ZFIN:ZDB-GENO-040929-2	Zfish	PMID:19652097
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	Esco2	IGI	MGI:MGI:1343184	Mouse	PMID:24029230
Biological Process	GO:0000278	mitotic cell cycle	esco2	IMP	ZFIN:ZDB-MRPHLNO-110713-1	Zfish	PMID:21637801
Biological Process	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	esco2	IMP	ZFIN:ZDB-MRPHLNO-110713-1	Zfish	PMID:21637801
Biological Process	GO:0034421	post-translational protein acetylation	ESCO2	IMP		Human	PMID:21111234
Biological Process	GO:0071168	protein localization to chromatin	Esco2	IMP	MGI:MGI:5308063	Mouse	PMID:22101327
Biological Process	GO:0006275	regulation of DNA replication	ESCO2	IMP		Human	PMID:19907496
Biological Process	GO:0007062	sister chromatid cohesion	esco2	IMP	ZFIN:ZDB-GENO-151223-1	Zfish	PMID:26044958

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern