Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ERF
  • Mouse genes Erf
  • Rat genes Erf
  • Zfish genes erf,erfl3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Erf

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	ERF	IDA		Human	PMID:7588608
Molecular Function	GO:0005515	protein binding	ERF	IPI	UniProtKB:Q08117-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ERF	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ERF	IPI	UniProtKB:Q96EZ8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ERF	IPI	UniProtKB:Q9UGI0	Human	PMID:32296183
Molecular Function	GO:0043565	sequence-specific DNA binding	ERF	IDA		Human	PMID:23332764
Cellular Component	GO:0005829	cytosol	ERF	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	ERF	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Erf	IDA		Mouse	PMID:17502352
Biological Process	GO:0060710	chorio-allantoic fusion	Erf	IMP	MGI:MGI:3719472	Mouse	PMID:17502352
Biological Process	GO:0010668	ectodermal cell differentiation	Erf	IMP	MGI:MGI:3719472	Mouse	PMID:17502352
Biological Process	GO:0001701	in utero embryonic development	Erf	IMP	MGI:MGI:3719472	Mouse	PMID:17502352
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ERF	IDA		Human	PMID:7588608
Biological Process	GO:0060707	trophoblast giant cell differentiation	Erf	IMP	MGI:MGI:3719472	Mouse	PMID:17502352

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern