Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EPX
  • Mouse genes Epx
  • Rat genes Epx
  • Zfish genes mpx
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Epx

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004601	peroxidase activity	Epx	IDA		Mouse	PMID:8773591
Molecular Function	GO:0004601	peroxidase activity	Epx	IDA		Mouse	PMID:16926417
Molecular Function	GO:0004601	peroxidase activity	mpx	IDA		Zfish	PMID:22940471
Cellular Component	GO:0005737	cytoplasm	mpx	IDA		Zfish	PMID:19097072
Cellular Component	GO:0005737	cytoplasm	mpx	IDA		Zfish	PMID:11698295
Cellular Component	GO:0070062	extracellular exosome	EPX	HDA		Human	PMID:23533145
Biological Process	GO:0002215	defense response to nematode	Epx	IMP	MGI:MGI:2182952	Mouse	PMID:16926417
Biological Process	GO:0072677	eosinophil migration	Epx	IMP	MGI:MGI:2182952	Mouse	PMID:16926417
Biological Process	GO:0006954	inflammatory response	mpx	IMP	ZFIN:ZDB-GENO-150702-1	Zfish	PMID:25665803
Biological Process	GO:0032613	interleukin-10 production	Epx	IMP	MGI:MGI:2182952	Mouse	PMID:16926417
Biological Process	GO:0032633	interleukin-4 production	Epx	IMP	MGI:MGI:2182952	Mouse	PMID:16926417
Biological Process	GO:0032634	interleukin-5 production	Epx	IMP	MGI:MGI:2182952	Mouse	PMID:16926417
Biological Process	GO:0010934	macrophage cytokine production	Epx	IMP	MGI:MGI:2182952	Mouse	PMID:16926417
Biological Process	GO:0032693	negative regulation of interleukin-10 production	Epx	IMP	MGI:MGI:2182952	Mouse	PMID:16926417
Biological Process	GO:0032714	negative regulation of interleukin-5 production	Epx	IMP	MGI:MGI:2182952	Mouse	PMID:16926417
Biological Process	GO:0010936	negative regulation of macrophage cytokine production	Epx	IMP	MGI:MGI:2182952	Mouse	PMID:16926417
Biological Process	GO:0032753	positive regulation of interleukin-4 production	Epx	IMP	MGI:MGI:2182952	Mouse	PMID:16926417
Biological Process	GO:0010310	regulation of hydrogen peroxide metabolic process	mpx	IMP	ZFIN:ZDB-GENO-121213-40	Zfish	PMID:22940471
Biological Process	GO:0009617	response to bacterium	mpx	IDA		Zfish	PMID:17055441
Biological Process	GO:0009617	response to bacterium	mpx	IDA		Zfish	PMID:17804254

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern