Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EPN1
  • Mouse genes Epn1
  • Rat genes Epn1
  • Zfish genes epn1a,epn1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Epn1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035615	clathrin adaptor activity	Epn1	IMP		Rat	PMID:11756460|RGD:12793027
Molecular Function	GO:0060090	molecular adaptor activity	Epn1	EXP		Rat	PMID:11756460|RGD:12793027
Molecular Function	GO:0140313	molecular sequestering activity	EPN1	EXP		Human	PMID:11161217
Molecular Function	GO:0140313	molecular sequestering activity	EPN1	IPI	ChEBI:18348	Human	PMID:11161217
Molecular Function	GO:0005515	protein binding	EPN1	IPI	UniProtKB:Q9UHD9	Human	PMID:18199683
Molecular Function	GO:0005515	protein binding	EPN1	IPI	UniProtKB:P42566	Human	PMID:18200045
Molecular Function	GO:0005515	protein binding	EPN1	IPI	UniProtKB:Q15038	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EPN1	IPI	UniProtKB:Q96CS7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EPN1	IPI	UniProtKB:Q15884	Human	PMID:34927784
Molecular Function	GO:0005515	protein binding	EPN1	IPI	UniProtKB:P42566	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	Epn1	IPI	UniProtKB:P39083	Rat	PMID:16537494|RGD:13432312
Molecular Function	GO:0005515	protein binding	Epn1	IPI	UniProtKB:Q06407	Rat	PMID:16537494|RGD:13432312
Molecular Function	GO:0005515	protein binding	Epn1	IPI	UniProtKB:P97677	Rat	PMID:22658936|RGD:10402035
Molecular Function	GO:0044325	transmembrane transporter binding	Epn1	IPI	RGD:68398	Rat	PMID:10559257|RGD:9693722
Cellular Component	GO:0005829	cytosol	Epn1	IDA		Rat	PMID:11756460|RGD:12793027
Cellular Component	GO:0005634	nucleus	Epn1	IDA		Rat	PMID:19191224|RGD:2312786
Cellular Component	GO:0005886	plasma membrane	Epn1	IDA		Rat	PMID:16320245|RGD:11567253
Cellular Component	GO:0098794	postsynapse	Epn1	IDA		Rat	PMID:16320245|RGD:11567253
Cellular Component	GO:0045211	postsynaptic membrane	Epn1	IDA		Rat	PMID:16320245|RGD:11567253
Cellular Component	GO:0098793	presynapse	Epn1	IDA		Rat	PMID:16320245|RGD:11567253
Cellular Component	GO:0042734	presynaptic membrane	Epn1	IDA		Rat	PMID:16320245|RGD:11567253
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Epn1	IDA		Rat	PMID:16320245|RGD:11567253
Cellular Component	GO:0043195	terminal bouton	Epn1	HDA		Rat	PMID:24876496|RGD:10047219
Biological Process	GO:0048568	embryonic organ development	Epn1	IGI	MGI:MGI:1333766	Mouse	PMID:19666558
Biological Process	GO:0006897	endocytosis	Epn1	IDA		Rat	PMID:12353027|RGD:632726
Biological Process	GO:0007565	female pregnancy	Epn1	IGI	MGI:MGI:1333766	Mouse	PMID:19666558
Biological Process	GO:0001701	in utero embryonic development	Epn1	IGI	MGI:MGI:1333766	Mouse	PMID:19666558
Biological Process	GO:0090148	membrane fission	Epn1	IDA		Rat	PMID:25799353|RGD:15023484
Biological Process	GO:1903671	negative regulation of sprouting angiogenesis	EPN1	IGI	UniProtKB:O95208	Human	PMID:28717225
Biological Process	GO:0007219	Notch signaling pathway	Epn1	IGI	MGI:MGI:1333766	Mouse	PMID:19666558
Biological Process	GO:1905445	positive regulation of clathrin coat assembly	Epn1	IMP		Rat	PMID:11756460|RGD:12793027

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern