Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EPB41L3
  • Mouse genes Epb41l3
  • Rat genes Epb41l3
  • Zfish genes epb41l3a,epb41l3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Epb41l3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	EPB41L3	IPI	UniProtKB:Q9BY67	Human	PMID:12234973
Molecular Function	GO:0005515	protein binding	Epb41l3	IPI	UniProtKB:O54991	Mouse	PMID:21632923
Cellular Component	GO:0030673	axolemma	Epb41l3	IDA		Mouse	MGI:MGI:5296417|PMID:21966409
Cellular Component	GO:0030054	cell junction	EPB41L3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005911	cell-cell junction	EPB41L3	IDA		Human	PMID:12234973
Cellular Component	GO:0044224	juxtaparanode region of axon	Epb41l3	IDA		Mouse	MGI:MGI:2675529|PMID:12975355
Cellular Component	GO:0044224	juxtaparanode region of axon	Epb41l3	IDA		Mouse	MGI:MGI:3621602|PMID:16551741
Cellular Component	GO:0044224	juxtaparanode region of axon	Epb41l3	IDA		Mouse	MGI:MGI:5296417|PMID:21966409
Cellular Component	GO:0033270	paranode region of axon	Epb41l3	IDA		Mouse	MGI:MGI:3621602|PMID:16551741
Cellular Component	GO:0033270	paranode region of axon	Epb41l3	IDA		Mouse	MGI:MGI:5296417|PMID:21966409
Cellular Component	GO:0033270	paranode region of axon	Epb41l3	IDA		Mouse	MGI:MGI:2675529|PMID:12975355
Cellular Component	GO:0033270	paranode region of axon	Epb41l3	IDA		Rat	PMID:11146105|RGD:11252103
Cellular Component	GO:0005886	plasma membrane	EPB41L3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0014069	postsynaptic density	Epb41l3	IDA		Mouse	PMID:17114649
Biological Process	GO:0061564	axon development	Epb41l3	IMP	MGI:MGI:5140703	Mouse	PMID:21632923
Biological Process	GO:0043217	myelin maintenance	Epb41l3	IMP		Mouse	MGI:MGI:5296417|PMID:21966409
Biological Process	GO:0048812	neuron projection morphogenesis	Epb41l3	IMP		Mouse	MGI:MGI:5296417|PMID:21966409
Biological Process	GO:0030913	paranodal junction assembly	Epb41l3	IMP		Mouse	MGI:MGI:5296417|PMID:21966409
Biological Process	GO:1990227	paranodal junction maintenance	Epb41l3	IMP	MGI:MGI:5140703	Mouse	PMID:21632923
Biological Process	GO:0071205	protein localization to juxtaparanode region of axon	Epb41l3	IMP		Mouse	MGI:MGI:5296417|PMID:21966409
Biological Process	GO:0071205	protein localization to juxtaparanode region of axon	Epb41l3	IMP	MGI:MGI:5140703	Mouse	PMID:21632923
Biological Process	GO:0002175	protein localization to paranode region of axon	Epb41l3	IMP		Mouse	MGI:MGI:5296417|PMID:21966409
Biological Process	GO:0002175	protein localization to paranode region of axon	Epb41l3	IMP	MGI:MGI:5140703	Mouse	PMID:21632923
Biological Process	GO:0072659	protein localization to plasma membrane	Epb41l3	IMP		Mouse	MGI:MGI:5296417|PMID:21966409
Biological Process	GO:0008360	regulation of cell shape	Epb41l3	IMP		Mouse	MGI:MGI:5296417|PMID:21966409
Biological Process	GO:1904889	regulation of excitatory synapse assembly	epb41l3a	IMP	ZFIN:ZDB-MRPHLNO-190123-1	Zfish	PMID:30286167

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern