Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ELF5
  • Mouse genes Elf5
  • Rat genes Elf5
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Elf5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Elf5	IDA		Mouse	MGI:MGI:1316566|PMID:9840936
Molecular Function	GO:0005515	protein binding	ELF5	IPI	UniProtKB:Q9NS18	Human	PMID:32296183
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Elf5	IDA		Mouse	MGI:MGI:1316566|PMID:9840936
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ELF5	IDA		Human	PMID:28473536
Cellular Component	GO:0005737	cytoplasm	Elf5	IDA		Mouse	PMID:16469767
Cellular Component	GO:0005737	cytoplasm	Elf5	IDA		Mouse	PMID:24190884
Cellular Component	GO:0005634	nucleus	Elf5	IDA		Mouse	PMID:16469767
Biological Process	GO:0007398	ectoderm development	Elf5	IMP	MGI:MGI:3578666	Mouse	PMID:15829518
Biological Process	GO:0001712	ectodermal cell fate commitment	Elf5	IGI	MGI:MGI:95456	Mouse	PMID:25446535
Biological Process	GO:0060644	mammary gland epithelial cell differentiation	Elf5	IGI	MGI:MGI:97763	Mouse	PMID:16469767
Biological Process	GO:0060806	negative regulation of cell differentiation involved in embryonic placenta development	Elf5	IMP		Mouse	PMID:24859262
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Elf5	IDA		Mouse	MGI:MGI:1316566|PMID:9840936
Biological Process	GO:0035019	somatic stem cell population maintenance	Elf5	IMP		Mouse	PMID:24859262
Biological Process	GO:0060707	trophoblast giant cell differentiation	Elf5	IMP		Mouse	PMID:24859262

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern