Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EIF3B
  • Mouse genes Eif3b
  • Rat genes Eif3b
  • Zfish genes eif3ba
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Eif3b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	EIF3B	IPI	UniProtKB:Q14152	Human	PMID:11169732
Molecular Function	GO:0005515	protein binding	EIF3B	IPI	UniProtKB:O75821	Human	PMID:14688252
Molecular Function	GO:0005515	protein binding	EIF3B	IPI	UniProtKB:O75822	Human	PMID:14688252
Molecular Function	GO:0005515	protein binding	EIF3B	IPI	UniProtKB:Q13347	Human	PMID:14688252
Molecular Function	GO:0005515	protein binding	EIF3B	IPI	UniProtKB:Q14152	Human	PMID:14688252
Molecular Function	GO:0005515	protein binding	EIF3B	IPI	UniProtKB:Q9J0X9	Human	PMID:15567442
Molecular Function	GO:0005515	protein binding	EIF3B	IPI	UniProtKB:P23443	Human	PMID:18423201
Molecular Function	GO:0005515	protein binding	EIF3B	IPI	UniProtKB:O00303	Human	PMID:18599441
Molecular Function	GO:0005515	protein binding	EIF3B	IPI	UniProtKB:O15372	Human	PMID:18599441
Molecular Function	GO:0005515	protein binding	EIF3B	IPI	UniProtKB:O75821	Human	PMID:18599441
Molecular Function	GO:0005515	protein binding	EIF3B	IPI	UniProtKB:P60228	Human	PMID:18599441
Molecular Function	GO:0005515	protein binding	EIF3B	IPI	UniProtKB:Q13347	Human	PMID:18599441
Molecular Function	GO:0005515	protein binding	EIF3B	IPI	UniProtKB:Q14152	Human	PMID:18599441
Molecular Function	GO:0005515	protein binding	EIF3B	IPI	UniProtKB:Q7L2H7	Human	PMID:18599441
Molecular Function	GO:0005515	protein binding	EIF3B	IPI	UniProtKB:Q9UBQ5	Human	PMID:18599441
Molecular Function	GO:0005515	protein binding	EIF3B	IPI	UniProtKB:Q9Y262	Human	PMID:18599441
Molecular Function	GO:0005515	protein binding	EIF3B	IPI	UniProtKB:O00303	Human	PMID:18628297
Molecular Function	GO:0005515	protein binding	EIF3B	IPI	UniProtKB:O00571	Human	PMID:18628297
Molecular Function	GO:0005515	protein binding	EIF3B	IPI	UniProtKB:O15372	Human	PMID:18628297
Molecular Function	GO:0005515	protein binding	EIF3B	IPI	UniProtKB:O75821	Human	PMID:18628297
Molecular Function	GO:0005515	protein binding	EIF3B	IPI	UniProtKB:O75822	Human	PMID:18628297
Molecular Function	GO:0005515	protein binding	EIF3B	IPI	UniProtKB:P60228	Human	PMID:18628297
Molecular Function	GO:0005515	protein binding	EIF3B	IPI	UniProtKB:Q13347	Human	PMID:18628297
Molecular Function	GO:0005515	protein binding	EIF3B	IPI	UniProtKB:Q14152	Human	PMID:18628297
Molecular Function	GO:0005515	protein binding	EIF3B	IPI	UniProtKB:Q9UBQ5	Human	PMID:18628297
Molecular Function	GO:0005515	protein binding	EIF3B	IPI	UniProtKB:O00303	Human	PMID:19245811
Molecular Function	GO:0005515	protein binding	EIF3B	IPI	UniProtKB:Q14152	Human	PMID:19245811
Molecular Function	GO:0005515	protein binding	EIF3B	IPI	UniProtKB:O15372	Human	PMID:19615732
Molecular Function	GO:0005515	protein binding	EIF3B	IPI	UniProtKB:P23443	Human	PMID:21986499
Molecular Function	GO:0005515	protein binding	EIF3B	IPI	UniProtKB:O00303	Human	PMID:24396066
Molecular Function	GO:0005515	protein binding	EIF3B	IPI	UniProtKB:O75821	Human	PMID:24396066
Molecular Function	GO:0005515	protein binding	EIF3B	IPI	UniProtKB:Q14103	Human	PMID:24423872
Molecular Function	GO:0005515	protein binding	EIF3B	IPI	UniProtKB:O75821	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	Eif3b	IPI	UniProtKB:Q6NZJ6	Mouse	MGI:MGI:3628832|PMID:16541103
Molecular Function	GO:0005515	protein binding	Eif3b	IPI	UniProtKB:Q9R0N3	Rat	PMID:24882364|RGD:8693368
Molecular Function	GO:0003723	RNA binding	EIF3B	IDA		Human	PMID:25849773
Molecular Function	GO:0003723	RNA binding	EIF3B	IDA		Human	PMID:27462815
Molecular Function	GO:0003743	translation initiation factor activity	EIF3B	IDA		Human	PMID:17581632
Molecular Function	GO:0003743	translation initiation factor activity	EIF3B	IDA		Human	PMID:25849773
Molecular Function	GO:0003743	translation initiation factor activity	EIF3B	IDA		Human	PMID:8995410
Molecular Function	GO:0003743	translation initiation factor activity	Eif3b	IDA		Mouse	MGI:MGI:3843422|PMID:17581632
Cellular Component	GO:0010494	cytoplasmic stress granule	EIF3B	IDA		Human	PMID:17984221
Cellular Component	GO:0005852	eukaryotic translation initiation factor 3 complex	EIF3B	IPI		Human	PMID:17322308
Cellular Component	GO:0005852	eukaryotic translation initiation factor 3 complex	EIF3B	IDA		Human	PMID:17322308
Cellular Component	GO:0005852	eukaryotic translation initiation factor 3 complex	EIF3B	IDA		Human	PMID:17581632
Cellular Component	GO:0005852	eukaryotic translation initiation factor 3 complex	EIF3B	IDA		Human	PMID:18599441
Cellular Component	GO:0005852	eukaryotic translation initiation factor 3 complex	EIF3B	IDA		Human	PMID:25849773
Cellular Component	GO:0005852	eukaryotic translation initiation factor 3 complex	EIF3B	IDA		Human	PMID:8995410
Cellular Component	GO:0005852	eukaryotic translation initiation factor 3 complex	Eif3b	IDA		Mouse	MGI:MGI:3843422|PMID:17581632
Cellular Component	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m	Eif3b	IDA		Mouse	PMID:24003236
Cellular Component	GO:0070062	extracellular exosome	EIF3B	HDA		Human	PMID:20458337
Cellular Component	GO:0045202	synapse	Eif3b	EXP		Mouse	PMID:25211037
Cellular Component	GO:0045202	synapse	Eif3b	IDA		Mouse	PMID:25211037
Cellular Component	GO:0045202	synapse	Eif3b	EXP		Mouse	PMID:16452087
Cellular Component	GO:0045202	synapse	Eif3b	IDA		Mouse	PMID:16452087
Biological Process	GO:0003313	heart rudiment development	eif3ba	IMP		Zfish	PMID:23791820
Biological Process	GO:0075522	IRES-dependent viral translational initiation	EIF3B	IDA		Human	PMID:9573242
Biological Process	GO:0014032	neural crest cell development	eif3ba	IMP	ZFIN:ZDB-GENO-140109-79	Zfish	PMID:23791820
Biological Process	GO:0006446	regulation of translational initiation	EIF3B	IDA		Human	PMID:8995410
Biological Process	GO:0006413	translational initiation	EIF3B	IDA		Human	PMID:17581632
Biological Process	GO:0006413	translational initiation	EIF3B	IDA		Human	PMID:8995410
Biological Process	GO:0006413	translational initiation	Eif3b	IDA		Mouse	MGI:MGI:3843422|PMID:17581632
Biological Process	GO:0075525	viral translational termination-reinitiation	EIF3B	IDA		Human	PMID:21347434

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern