Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EIF2S3,EIF2S3B
  • Mouse genes Eif2s3x
  • Rat genes Eif2s3
  • Zfish genes eif2s3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Eif2s3x

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	EIF2S3	HDA		Human	PMID:25468996
Molecular Function	GO:0005515	protein binding	EIF2S3	IPI	UniProtKB:P05198	Human	PMID:16288713
Molecular Function	GO:0005515	protein binding	EIF2S3	IPI	UniProtKB:P20042	Human	PMID:16288713
Molecular Function	GO:0005515	protein binding	EIF2S3	IPI	UniProtKB:P20042	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	EIF2S3	IPI	UniProtKB:A0A024RCP2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EIF2S3	IPI	UniProtKB:A6NJ78-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EIF2S3	IPI	UniProtKB:O15534	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EIF2S3	IPI	UniProtKB:O60506-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EIF2S3	IPI	UniProtKB:P38936	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EIF2S3	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EIF2S3	IPI	UniProtKB:P49459	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EIF2S3	IPI	UniProtKB:Q06547-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EIF2S3	IPI	UniProtKB:Q06547-3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EIF2S3	IPI	UniProtKB:Q0VD86	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EIF2S3	IPI	UniProtKB:Q3KNS6-3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EIF2S3	IPI	UniProtKB:Q496A3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EIF2S3	IPI	UniProtKB:Q53R41	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EIF2S3	IPI	UniProtKB:Q6DHV7-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EIF2S3	IPI	UniProtKB:Q6GQQ9-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EIF2S3	IPI	UniProtKB:Q7Z6I5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EIF2S3	IPI	UniProtKB:Q7Z7C8-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EIF2S3	IPI	UniProtKB:Q8N2H9-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EIF2S3	IPI	UniProtKB:Q8TBE0	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EIF2S3	IPI	UniProtKB:Q92615	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EIF2S3	IPI	UniProtKB:Q92782-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EIF2S3	IPI	UniProtKB:Q96FT7-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EIF2S3	IPI	UniProtKB:Q99683	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EIF2S3	IPI	UniProtKB:Q9BRR0	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EIF2S3	IPI	UniProtKB:Q9H1D9	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EIF2S3	IPI	UniProtKB:Q9HD47-3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EIF2S3	IPI	UniProtKB:Q9NS23-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EIF2S3	IPI	UniProtKB:Q9NX94	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Eif2s3	IPI	RGD:620963|RGD:735192	Rat	PMID:2450747|RGD:10395356
Molecular Function	GO:0008135	translation factor activity, RNA binding	EIF2S3	IDA		Human	PMID:10900014
Molecular Function	GO:0003743	translation initiation factor activity	EIF2S3	IDA		Human	PMID:10900014
Molecular Function	GO:0003743	translation initiation factor activity	EIF2S3	IDA		Human	PMID:16289705
Cellular Component	GO:0005737	cytoplasm	EIF2S3	IDA		Human	PMID:12426392
Cellular Component	GO:0005850	eukaryotic translation initiation factor 2 complex	EIF2S3	IDA		Human	PMID:23063529
Cellular Component	GO:0070062	extracellular exosome	EIF2S3	HDA		Human	PMID:20458337
Cellular Component	GO:0045202	synapse	Eif2s3x	IDA		Mouse	PMID:25211037
Cellular Component	GO:0045202	synapse	Eif2s3x	EXP		Mouse	PMID:25211037
Biological Process	GO:0006413	translational initiation	EIF2S3	IDA		Human	PMID:10900014

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern